Scientist, Pharmacokinetics (Onsite)

MSD; West Point (PA); On-site; USD 87,000 - 137,000; Full time

Benefits offered by this job

Medical benefits

Retirement plan

Job summary

MSD is seeking a bioanalytical scientist to execute and troubleshoot quantitative bioanalytical methods for small molecules, peptides, and biologics using LC-MS and LBA platforms. You will contribute to drug discovery and early development, delivering high-quality data across PK/PD studies.

You will perform sample preparation, method validation, and data delivery while maintaining GMP-compliant lab practices and safety standards.

Qualifications

• Experience with Ligand Binding Assays (LBA).
• Ability to collaborate in multidisciplinary scientific teams.
• Strong written and verbal communication skills.
• Proficient with Microsoft Office and standard lab software.

Responsibilities

• Develop, validate and execute quantitative bioanalytical methods (LC-MS/MS, LBA).
• Generate, analyze and deliver bioanalytical data for PK/PD studies.
• Perform manual and automated sample prep and manage lab operations.

Skills

LBA experience

Teamwork

Communication

Microsoft Office

Education

Bachelor's degree

MS degree

Job description

Job Description The department of Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) is seeking a highly motivated bioanalytical scientist to contribute to our drug discovery and early pre‑clinical development efforts. The Scientist will be responsible for execution and troubleshooting of quantitative bioanalytical methods of small molecules, peptides, and large molecules (biologics), utilizing both LC-MS and Ligand Binding Assay (LBA) platforms to deliver high‑quality data that drives our pipeline forward.

Key Responsibilities

• Method Execution & Troubleshooting: Develop, validate, and execute robust quantitative bioanalytical methods using LC-MS/MS, Ligand Binding Assays (LBA), and/or hybrid LC-MS/LBA workflows to support discovery and early development programs.
• Data Delivery: Generate, analyze, and deliver high‑quality bioanalytical data for PK, PD, and in vitro studies of both small and large molecule therapeutics within established timelines.
• Sample Preparation: Perform manual and automated sample preparation (e.g., protein precipitation, solid‑phase extraction, immunocapture/affinity purification for biological matrices).
• Lab Operations & Compliance: Maintain laboratory equipment and ensure all operations strictly adhere to safety, internal SOPs, and regulatory guidelines.
• Automation Integration: Support high‑throughput workflows by operating and troubleshooting robotics and automated systems.

Education

Minimum Requirement: Bachelor’s degree with 3+ years relevant laboratory experience or MS degree (1-2 years relevant experience) in analytical chemistry, pharmaceutical sciences, pharmacology, biomedical, chemical engineering or related field.

Required Experience & Skills

• Large Molecule & LBA Experience: Experience with Ligand Binding Assays (LBA) quantitation of large molecules/biologics.
• Teamwork & Interpersonal Skills: Demonstrated ability to collaborate effectively within high‑performing, multidisciplinary scientific teams.
• Communication: Excellent written and verbal communication skills, with the ability to present scientific data clearly.
• Technical Proficiency: Proficient in Microsoft Office Suite (Excel, Word, PowerPoint) and standard laboratory software.

Preferred Skills

• Data Analysis: A basic understanding of statistical analysis and pharmacokinetic principles.
• Small Molecule & Peptide Analysis: Experience with liquid chromatography (LC) and mass spectrometry (MS) for the quantitative analysis of small molecules and/or peptides in biological matrices.

Additional Required Skills

• Bioanalysis
• Biochemistry
• Biotherapeutics
• Cell Culture Techniques
• Ethical Compliance
• GMP Documentation
• Good Laboratory Practices (GLPs)
• Immunoassays
• Laboratory Instrumentation
• Laboratory Management
• Laboratory Safety
• Liquid Chromatography‑Mass Spectrometry (LC‑MS)
• Pharmaceutical Sciences
• Pharmacodynamics
• Pharmacokinetics
• Pharmacology
• Small Molecules

Equal Employment Opportunity

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement.

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts.

Location & Compensation

Primary location: USA - Pennsylvania - West Point.

Salary range for the primary location of this role is: $87,300.00 - $137,400.00.

An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long‑term incentive, if applicable.

Benefits

• Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.

Additional location(s): Please note the salary range above applies to the Primary Location of the position. Where a role has other listed locations, different compensation guidelines may apply. You may find the salary ranges for additional locations below. If the salary range is not listed for the location you are applying to, our Talent Acquisition team will provide further information to you relevant to your location.

Employment Details

Employee Status: Regular.

Relocation: Domestic.

VISA Sponsorship: No.

Travel Requirements: 10%.

Flexible Work Arrangements: Not Applicable.

Shift: Not Indicated.

Valid Driving License: No.

Hazardous Material(s): Biological matrices.

Job Posting End Date: 11/2/2026. *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century. Our success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.