Scientist – Inflammation Research

Amgen Inc.; Thousand Oaks (CA); Hybrid; USD 115,000 - 156,000; Full time

Benefits offered by this job

Retirement and Savings Plan with group

Medical, Dental, Vision coverage

Life and Disability Insurance

Stock-based long-term incentives

Flexible time-off plans

Job summary

Amgen Inc. in Thousand Oaks, CA seeks a scientist to perform in vitro and in vivo experiments, including organoid and air-liquid interface cultures, to test novel inflammatory targets. You will analyze lung epithelium function and collaborate across Amgen teams.

The role emphasizes 2D/3D cell cultures, mouse disease models, and strong publication contributions, with flexible work options and competitive benefits.

Qualifications

• Doctorate or equivalent with research experience in biology and inflammation.
• Experience in both in vitro and in vivo experiments.
• Strong publication record or significant contributions to therapeutic development programs.

Responsibilities

• Perform both in vitro and in vivo experiments to generate high-quality data.
• Support target identification, validation and progression in inflammation programs.
• Propose drug targets for respiratory diseases using human genetics and literature.
• Apply AI-driven approaches to gain mechanistic insights and guide experiments.
• Publish and present findings at scientific conferences.

Skills

In vitro experiments

In vivo experiments

2D/3D cell cultures

Mouse disease models

Pulmonary mechanics

Publishing experience

Education

Doctorate degree

Master’s degree + 2 years experience in Biological Sciences / Biomedical Sciences

Bachelor’s degree + 4 years experience in Biological Sciences / Biomedical Sciences

Job description

What you will do

Let’s do this. Let’s change the world. In this vital role you will perform in vitro and in vivo experiments- including determination of effects of drug targets using organoid and air liquid interface primary cell cultures and testing novel drug targets in mouse models of inflammatory disease.

This position will also involve analysis of lung epithelium function, repair, and regeneration. You will collaborate with a dynamic research team from multiple Amgen functional areas.

Key Responsibilities

• Perform both in vitro and in vivo experiments.
• Generate high-quality experimental data to support target identification, validation and progression of Inflammation research programs.
• Propose drug targets for respiratory diseases integrating human genetics, in vitro/in vivo studies, and published literature.
• Use AI-driven approaches to generate mechanistic insights, refine therapeutic hypotheses, and guide experimental design.
• Ability to balance scientific rigor with urgency and adaptability in a dynamic research environment.
• Publish and present at conferences.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a researcher with these qualifications.

Basic Qualifications

• Doctorate degree
• OR
• Master’s degree and 2 years of Biological Sciences / Biomedical Sciences experience
• OR
• Bachelor’s degree and 4 years of Biological Sciences / Biomedical Sciences experience

Preferred Qualifications

• PhD with strong background and research experience in epithelial biology and inflammation.
• Experience performing both in vitro and in vivo experiments.
• Expertise in 2D and 3D primary cell cultures / co-cultures / human tissue cultures and mouse disease models.
• Technical expertise in mouse respiratory disease models and measurement of pulmonary mechanics.
• Strong publication record or significant contributions to therapeutic development programs.

What you can expect of us

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long‑term incentives
• Award‑winning time‑off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted.

115,393.45USD -156,120.55 USD

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.

Sponsorship for this role is not guaranteed.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline: Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.