Scientist, In Vivo CAR-T Therapy

BioNJ Inc.; Philadelphia (Philadelphia County); Sur place; USD 108 000 - 132 000; Plein temps

Avantages offerts par ce poste

Permanent full-time benefits

Résumé du poste

Legend Biotech USA, Inc. is seeking a Scientist - In Vivo CAR-T Therapy in Philadelphia, PA. The role focuses on designing and executing studies to advance CAR-T platforms from discovery through preclinical development, with emphasis on in vivo work and assay development.

The candidate will collaborate with internal teams, interpret complex data, and deliver high-quality reports supporting translational efforts in cell and gene therapy.

Qualifications

• PhD in Immunology, Biology, Biochemistry, Chemistry or a closely related field.
• 2 years of hands-on experience in cell and/or gene therapy research.

Responsabilités

• Design, plan, and execute experimental studies across in vivo CAR-T development.
• Evaluate product potency, efficacy, and safety through in vitro and in vivo studies.
• Develop and troubleshoot assays including ELISA, PCR, and viral vector work.
• Prepare clear, detailed technical reports and communicate results to teams.

Connaissances

Hands-on research experience

In vivo CAR-T development

Formation

PhD in Immunology or related field

Outils

PCR-based assays

Viral vector packaging

ELISA

Cell line engineering

Description du poste

COMPANY

Legend Biotech USA, Inc

JOB TITLE

Scientist - In Vivo CAR-T Therapy

JOB DUTIES

The Scientist - In Vivo CAR-T Therapy will have the following duties: Design, plan, and execute experimental studies to advance cell and gene therapy platforms and pipeline programs, with a focus on in vivo CAR T development from early discovery through preclinical development. Conduct and analyze in vitro and in vivo studies to evaluate product potency, efficacy, and safety. Develop, optimize, validate, and troubleshoot experimental assays and laboratory methods, including cell line engineering, cell-based functional and cytotoxicity assays, ELISA and PCR-based assays, high-throughput binder screening, and viral vector packaging and titration. Analyze, interpret, and summarize complex scientific data generated from experimental studies and maintain accurate, complete, and well-organized experimental records and documentation. Prepare clear, detailed, and high-quality technical reports, summaries, and presentations to communicate research findings, experimental results, and scientific conclusions. Collaborate closely with internal research and early development teams in a cross-functional environment to support translation of novel scientific concepts into therapeutic candidates and advancement of cell and gene therapy research programs.

MINIMUM JOB REQUIREMENTS

Education Required: PhD in Immunology, Biology, Biochemistry, Chemistry or a closely related field.

Experience Required: 2 yrs of experience in hands on experience in cell and/or gene therapy research.

JOB SITE

2300 Market St., 3 rd Floor, Philadelphia, PA 19103

WORK HOURS

9:00 a.m. to 5:00 p.m. 5 days 40 hr/wk

SALARY

$119,692.00 per year

BENEFITS

Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life‑threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T‑cell (CAR‑T), T‑cell receptor (TCR‑T), natural killer (NK) cell‑based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting‑edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta‑cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

Work Authorization & Employment Eligibility

Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E‑Verify program. If you are selected for employment, you will be required to complete the Form I‑9 process, and your employment eligibility will be verified through E‑Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.

EEO Statement

It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.

Employment is at‑will and may be terminated at any time with or without cause or notice by the employee or the company.

For information related to our privacy notice, please review: Legend Biotech Privacy Notice .