Scientist III Cell Biology & Functional Genomics

The Fountain Group; Ridgefield (CT); On-site; USD 57,000 - 81,000; Full time

Job summary

The Fountain Group is seeking a Research Scientist – Cell Biology & Genomics in Ridgefield, CT. The role involves hands-on mammalian cell culture, cell-based assays, functional genomics, and automated workflows to support disease discovery projects.

Responsibilities include performing NGS library prep, tissue/cell dissociation, QC, and sequencing setup, along with DNA/RNA extraction, qPCR, and protein analysis. Collaboration with automation, genomics, and bioinformatics teams is required.

Qualifications

• Hands-on mammalian cell culture and cell-based assay execution.
• NGS workflows: tissue/cell/nuclei dissociation, library preparation, QC, quantification, normalization.
• Bulk RNA-seq, single-cell RNA-seq, or single-nucleus RNA-seq.
• Laboratory automation, automated instrumentation, or high-throughput workflows.
• DNA/RNA extraction, PCR, qPCR, nucleic acid/protein quantification, and Western blotting.
• Experimental sample tracking, electronic laboratory notebooks, and SOP-controlled documentation.

Responsibilities

• Support cardiovascular, renal, and metabolic disease discovery research through hands-on mammalian cell culture, cell-based assays, functional genomics, and laboratory automation.
• Execute automated cell culture and assay workflows and troubleshoot routine platform issues.
• Perform tissue, cell, and nuclei dissociation and NGS workflows, including library preparation, QC, quantification, normalization, and sequencing setup.
• Conduct DNA/RNA extraction, PCR, qPCR, protein quantification, Western blotting, and related molecular biology procedures.
• Maintain accurate sample, reagent, experimental metadata, and electronic laboratory notebook records in accordance with SOPs and data integrity requirements.
• Support iPSC-derived cell workflows and collaborate with cell biology, automation, genomics, and bioinformatics teams.

Skills

Mammalian cell culture

Cell-based assays

NGS workflows

Bulk RNA-seq

Single-cell RNA-seq

Laboratory automation

DNA/RNA extraction

PCR/qPCR

Western blotting

Electronic lab notebooks

Education

Bachelor’s or Master’s degree in Biology, Cell Biology, Molecular Biology, Genomics, Biotechnology, or related life sciences

Tools

Automated instrumentation

Sequencer operation

High-throughput workflows

Electronic laboratory notebooks

Job description

Research Scientist – Cell Biology & Genomics
Location:Ridgefield, CT
Pay Rate: $49.96/hr
Duration: 2 years

Job Description

• Support cardiovascular, renal, and metabolic disease discovery research through hands-on mammalian cell culture, cell-based assays, functional genomics, and laboratory automation.
• Execute automated cell culture and assay workflows and troubleshoot routine platform issues.
• Perform tissue, cell, and nuclei dissociation and NGS workflows, including library preparation, QC, quantification, normalization, and sequencing setup.
• Conduct DNA/RNA extraction, PCR, qPCR, protein quantification, Western blotting, and related molecular biology procedures.
• Maintain accurate sample, reagent, experimental metadata, and electronic laboratory notebook records in accordance with SOPs and data integrity requirements.
• Support iPSC-derived cell workflows and collaborate with cell biology, automation, genomics, and bioinformatics teams.

Education

• Bachelor’s or Master’s degree in Biology, Cell Biology, Molecular Biology, Genomics, Biotechnology, or a related life sciences field.

Required Skills

• Hands-on mammalian cell culture and cell-based assay execution
• NGS workflows: tissue/cell/nuclei dissociation, library preparation, QC, quantification, and normalization
• Bulk RNA-seq, single-cell RNA-seq, or single-nucleus RNA-seq
• Laboratory automation, automated instrumentation, or high-throughput workflows
• DNA/RNA extraction, PCR, qPCR, nucleic acid/protein quantification, and Western blotting
• Experimental sample tracking, electronic laboratory notebooks, and SOP-controlled documentation

Preferred Skills

• Laboratory automation platforms for cell-based or molecular assays
• Sequencing run setup and sequencer operation
• Human iPSC culture, differentiation, characterization, or iPSC-derived cell assays
• iPSC-derived kidney organoid culture systems
• Image-based cell analysis
• Functional genomics and target validation research