Scientist II – Senior Scientist, Biochemistry Integration

San Diego Stealth Startup; San Diego (CA); On-site; USD 113,000 - 140,000; Full time

Job summary

San Diego Stealth Startup in California seeks a Scientist II / Sr. Scientist, Biochemistry Integration to drive development and integration of reagents and assays on our platform.

You will optimize workflows and partner across teams to deliver robust, scalable solutions. The role offers broad technical growth, collaboration with engineers, chemists and data scientists, and opportunities to contribute to manuscripts and patents while maintaining safety and reproducibility in a dynamic lab

Qualifications

• Ph.D. in Biochemistry or related field or MS with 4+ years of experience, or BS with 6+ years of experience.
• Experience optimizing quantitative biochemical assays.
• Strong problem-solving, organizational, and communication skills.
• Ability to work independently and in cross-functional teams.
• Experience with reagent development for instrumentation is a plus.
• Interest in analysis of large datasets, scripting, or coding to interpret experiments is a plus.

Responsibilities

• Develop reagents and assay workflows; optimize robustness.
• Integrate reagents and workflows with prototype, pre-production and production instruments.
• Develop and validate analytical assays (plate reader, HPLC) to assess activity and stability.
• Collaborate with engineers, chemists, and data scientists to achieve goals.
• Design, execute and lead engineering studies and cross-functional collaborations.
• Communicate results clearly; prepare reports and manuscripts/patents.
• Document methods, prepare SOPs, and support lab organization and safety.

Skills

Problem-solving

Communication

Collaboration

Education

PhD or MSc in Biochem/Eng

Tools

HPLC

Plate reader

Instrumentation

Job description

Scientist II – Senior Scientist, Biochemistry Integration

Job Type: Full-Time

Compensation: $113,000 - $140,000

Position Overview

We are seeking a Scientist II / Sr. Scientist, Biochemistry Integration to play a key role in the development of novel assays. This individual will optimize and integrate reagents to achieve highest levels of system performance and robustness of the organization’s platform.

The role will contribute directly to development of reagents, workflow implementation, integration of reagents and workflows on our platform, and help define requirements for future platforms. This role offers opportunities for broad technical growth not only in core area of biochemistry integration but also on interfaces with departments across the organization.

The candidate must be an effective communicator, analytical, and collaborative, thriving in a dynamic environment that values innovation, cross-disciplinary interaction, and scientific rigor. The ideal candidate is curious and a fast learner, unintimidated by climbing steep new learning curves and going deep into the details of a new technology.

Key Responsibilities

• Develop reagents and assay workflows and perform formulation optimization, robustness.
• Integrate reagents and workflows with the company’s prototype, pre-production and production instruments. Run, troubleshoot and optimize workflows on our instruments.
• Develop, implement and validate analytical assays (plate reader, HPLC, etc.) to access activity, reaction kinetics, reagent and component stability.
• Collaborate closely with cross-disciplinary teams that include engineers, chemists, and data scientists to achieve company goals.
• Design, execute and lead engineering studies and initiate and contribute to cross-functional collaborations.
• Communicate results clearly, prepare scientific reports and presentations, and contribute to manuscripts/patents.
• Document methods, prepare reports, and contribute to SOPs.
• Support lab organization, formulate reagents, maintain equipment, ensure compliance with safety and reproducibility practices.

Qualifications

• Ph.D. in Biochemistry, Bioengineering, Chemistry, Molecular Biology, or related field with or M.S. with 4+ years of relevant experience, or B.S. with 6+ years of relevant experience.
• Demonstrated experience optimizing and implementing quantitative biochemical assays.
• Excellent problem-solving, organizational, and communication skills.
• Ability to work independently and collaboratively in cross-functional teams.
• Interest and willingness to work with instrument breadboards and development prototypes.
• Demonstrated motivation, curiosity, proactivity, and willingness to learn.
• Excellent problem-solving, organizational, and communication skills.
• Experience with development of reagents for instrumentation is a plus.
• Interest in analysis of large datasets, scripting, or modifying code to interpret experiments is a plus.

Why Join Us

• Influence the foundational technologies and strategies of a company poised to shape the future of healthcare.
• Work in a dynamic, collaborative environment where innovation and scientific rigor are deeply valued.
• Join a seasoned and multidisciplinary team tackling high-impact problems at the intersection of science and engineering.
• Competitive compensation and equity package, comprehensive benefits, and flexibility to support work-life integration.

We are an equal opportunity employer. We thrive on diversity and collaboration.