Scientist II

MilliporeSigma; San Diego (CA); On-site; USD 83,000 - 110,000; Part time

Job summary

MilliporeSigma is seeking a temporary contract on the Process and Analytical Development team at its viral vector CDMO facility in Carlsbad, CA. The role focuses on execution and development of analytical assays to support process development for innovative viral vector therapeutics.

The candidate will perform analytical testing using UHPLC, CE systems, and SEC-MALS/FFF-MALS, develop methods, generate worksheets and reports, and collaborate with internal and external partners to advance

Qualifications

• Bachelor’s or higher in chemistry/biochemistry or life sciences.
• 7+ years in biopharmaceutical industry.
• Master’s with 5+ years in biopharma.
• Ph.D. with 3+ years in biopharma.

Responsibilities

• Perform analytical testing with UHPLC, CE, and related systems.
• Develop methods for process development of viral vectors.
• Generate worksheets, reports, and method transfer documents.
• Communicate with internal and external partners on technical guidance.
• Independently design and execute experiments.
• Analyze complex data and interpret results.

Skills

Analytical testing

Method development

Data analysis

Technical communication

Education

Bachelor’s degree in chemistry/biochemistry/life sciences

Master’s degree in chemistry/biochemistry/life sciences

Ph.D. in chemistry/biochemistry/life sciences

Tools

Thermo Vanquish UHPLC

Sciex CE system BioPhase 8800

Wyatt SEC-MALS

FFF-MALS

Thermo Chromeleon

Job description

At MilliporeSigma, they are at the forefront of life sciences, working tirelessly to tackle the industry's toughest challenges. By collaborating with the global scientific community, they strive to enhance health access worldwide. Their mission is clear: to equip scientists and engineers with top-notch lab materials, technologies, and services, making research and biotech production simpler, faster, and more successful. With a dedication to shaping the future of drug development, they’re with our customers every step of the way, pioneering tomorrow’s possibilities.

MilliporeSigma is seeking to fill a temporary contracting role on the Process and Analytical Development team at its viral vector CDMO facility in Carlsbad, CA. The candidate will be responsible for the execution and development of analytical assays in support of process development activities for innovative viral vector therapeutics.

Key Responsibilities

• Perform analytical testing using Thermo Vanquish UHPLC, Sciex CE system BioPhase 8800, Wyatt SEC-MALS and FFF-MALS.
• Develop methods using Thermo Vanquish UHPLC system.
• Generate worksheets, summary reports, and method transfer documents.
• Interface effectively with both internal and external partners to communicate technical guidance and updates.
• Investigate, create, and develop new methods and technology to achieve technical objectives and advancement.
• Independently design, plan, and execute experiments.
• Independently analyze complex data and interpret results.
• Able to contribute to and execute technical transfers of analytical methods from and/or to internal and external partners.

Minimum Qualifications

• Bachelor’s degree in chemistry, biochemistry, or related life science studies.
• 7+ years of relevant experience in biopharmaceutical industry.
• OR
• Master’s degree in chemistry, biochemistry, or related life science studies.
• 5+ years of relevant experience in biopharmaceutical industry.
• OR
• Ph.D. in chemistry, biochemistry, or related life science studies.
• 3+ years of relevant experience in biopharmaceutical industry.

Preferred Qualifications

• Knowledge and technical expertise in biologics analytical techniques and method development with a focus on HPLC and CE.
• Highly experienced in using Thermo Vanquish UHPLC system and proficient in using Thermo Chromeleon software.
• Experience in using Sciex CE system BioPhase 8800 or PA 800 Plus.
• Experience in using Wyatt SEC-MALS and FFF-MALS.
• Highly detail oriented.
• Helpful to have academic and/or industry-based background in virology
• Critical and analytical thinking skills to effectively solve problems and improve outcomes.
• Effective communicator of scientific results
• Knowledge of quality systems within an FDA-regulated environment
• Knowledge of ICH quality guidelines
• Maintain laboratory equipment and ensure proper sample handling procedures are followed for accurate results.

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

Pay: $70.00 per hour

Application Question(s)

• Do you have professional experience performing analytical testing and method development using Thermo Vanquish UHPLC systems?" (Yes/No)
• "Do you have hands-on experience using Sciex CE systems (e.g., BioPhase 8800 or PA 800 Plus)?" (Yes/No)
• "Do you have experience using Wyatt SEC-MALS or FFF-MALS instrumentation?" (Yes/No)
• Are you proficient in using Thermo Chromeleon software for analytical data analysis?" (Yes/No)
• "What is the highest level of education you have completed in Chemistry, Biochemistry, or a related Life Science field?" (Please list your highest level along with years of relevant experience in the biopharmaceutical industry)
• "Do you have experience working with quality systems within an FDA-regulated environment and knowledge of ICH quality guidelines?" (Yes/No)
• "Do you have experience executing the technical transfer of analytical methods between internal or external partners?" (Yes/No)