Scientist I/II (Cell Culture)

R&D Partners; South San Francisco (CA); On-site; USD 59,000 - 65,000; Full time

Benefits offered by this job

Medical insurance

401k plan

Employee Assistance Program

Long-term disability

Weekly payroll

Online timecard approval

Job summary

R&D Partners in South San Francisco, CA seeks a Scientist I/II to support our biotechnology client’s safety assessment programs across drug discovery through clinical development. This lab-based role involves hands-on biology, collaborating across teams to unravel mechanisms of toxicity using in vitro and ex vivo approaches.

The candidate will culture and expand primary cells and cell lines, perform cytotoxicity and metabolic assays, and contribute data-driven insights for peer-reviewed

Qualifications

• Bachelor's degree in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related field.
• 1–3+ years of laboratory experience with hypothesis-driven research.
• Experience with immortalized and/or primary cell culture and cell viability assays.
• Experience with Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry.
• Ability to analyze, integrate, and present data in a clear format.

Responsibilities

• Perform and implement biological assays using cell culture and related technologies.
• Culture and expand primary cells and cell lines for in vitro screenings.
• Conduct cytotoxicity and metabolic assessments; capture cell images; analyze data.
• Contribute scientific insights to projects and peer-reviewed publications.
• Collaborate across teams with strong communication and learning mindset.

Skills

Cell culture

Data analysis

Present findings

Team collaboration

Hypothesis-driven research

Education

Bachelor's degree

Master's degree desirable

Tools

Luminex/ELISAs

Confocal microscopy

Flow cytometry

High content screening

Cell viability assays

Gene expression analysis

Job description

We are hiring a Scientist I/II to join our biotechnology client's Research organization. The mission of this group is to elucidate the mechanisms underlying toxicities that are observed non-clinically and/or in clinical trials through hypothesis driven research. This process involves closely collaborating with scientists across the organization to support the overall safety assessment for our novel therapeutics spanning drug discovery through clinical development and marketing. The group provides fit-for-purpose wet lab-based investigation to address target safety assessment, lead optimization, and issue mitigation by employing state-of-the-science in vitro and ex vivo approaches. As such, we are constantly establishing new platforms and technologies to support a constantly changing portfolio, novel modalities, and emerging therapeutic area needs.

This is a 12 month contract position in South San Francisco, CA.

Responsibilities

• This laboratory-based role involves performing, qualifying, and implementing biological assays and technologies.
• This individual must have experience in cell culture and will be responsible for culturing and expanding primary cells and cell lines for in vitro screenings and performing assays which may include assessments of cytotoxicity and metabolic changes of cells, capturing cell culture images using high content imaging, flow cytometry, and other technologies.
• This individual will be working with cells from a broad range of tissues (immune cells, blood, liver, vascular, ocular, immortalized cell lines) and is expected to make detailed observations related to experiments, perform, analyze data, and interpret results.
• This individual will contribute scientific insights and work in projects related to peer review publications.
• This is an ideal position for a researcher who is enthusiastic about learning and contributing to projects with a broad range of techniques. As such the position requires excellent communication and collaboration skills, a desire to learn about and integrate multiple aspects of drug toxicity, and a passion for lab-based research.

Qualifications

• Bachelors (BS/BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required; Masters (MS) degree is desirable, but not required.
• 1-3+ years of laboratory experience with hypothesis-driven research.
• Ability to analyze, integrate, and present data in a presentation is required.
• Experience with immortalized and/or primary cell culture, cell viability assessment, Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry is highly desired.
• Experience with complex in-vitro model systems is highly desired.
• Role will Involve:
• Sitting or standing for extended periods.
• Performing repetitive tasks such as cell culture, pipetting and labeling tubes.
• Work with potentially hazardous materials including (but not limited to): chemotherapeutics, biological hazards, and human primary cells.

Pay

• $42.55-$47.05/hr

Why Choose R&D Partners?

As an employee, you have access to a comprehensive benefits package including:

• Medical insurance – PPO, HMO & HSA
• 401k plan
• Employee Assistance Program
• Long-term disability
• Weekly payroll
• Online timecard approval

R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.

R&D Partners is an equal-opportunity employer.