Scientist I

WuXi AppTec; San Diego (CA); On-site; USD 69,000 - 90,000; Full time

Job summary

HD Biosciences Inc. a WuXi AppTec company is seeking a histology specialist to perform fixation, processing, embedding, microtomy, and slide preparation. You will stain with H&E and IHC/IF, handle diverse tissue types, and collaborate with in vivo pharmacology to support tissue evaluation.

Role requires PhD or advanced degree with hands-on histology experience; strong documentation, communication, and problem-solving skills are essential for generating high-quality, reproducible data.

Qualifications

• PhD or advanced degree in Histology, Pathology, Biomedical Sciences, or related field.
• Hands-on histology/histopathology lab experience required.
• Strong documentation and data recording capabilities.

Responsibilities

• Perform hands-on histology procedures: fixation, processing, embedding, microtomy, slide prep.
• Conduct H&E, IHC, IF stains; RNAscope as applicable.
• Manage tissue types and specimens per protocols; support in vivo pharmacology team.
• Troubleshoot tissue processing and staining; maintain study records and data.
• Develop/validate histology protocols; summarize findings for reports.

Skills

Histology techniques

Tissue processing

IHC/IF

Microscopy

Attention to detail

Documentation

Education

PhD or advanced degree

Tools

Microsoft Office

Job description

HD Biosciences Inc. a WuXi AppTec company, offers biology-focused preclinical drug discovery services to biotech and pharmaceuticals. We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, in vivo pharmacology, as well as other research and development services.

• Perform hands-on histology procedures, including tissue fixation, processing, paraffin embedding, microtomy, and slide preparation.
• Perform routine and special histological stains, including H&E, immunohistochemistry (IHC) and immunofluorescence (IF) assays, RNAscope, as applicable.
• Handle and process a variety of animal and human tissue types and biological specimens according to established protocols.
• Work closely with in vivo pharmacology team to support tissue evaluation.
• Troubleshoot tissue processing, sectioning, staining, and IHC-related issues and implement appropriate corrective actions.
• Maintain accurate laboratory records, study documentation, sample tracking, and experimental data.
• Develop, optimize, and validate histology and staining protocols when required.
• Analyze and summarize histological findings and contribute to study reports, presentations, and scientific documentation.
• Master’s or Ph.D. in Histology, Pathology, Biomedical Sciences, or a related field.
• Demonstrated hands‑on experience in histology/histopathology laboratory techniques.
• Strong practical experience with:
• Tissue fixation and processing
• Paraffin embedding
• Microtomy and tissue sectioning
• H&E staining
• Slide preparation and quality assessment
• Microscopic evaluation of tissue morphology
• Experience with special stains and / or immunohistochemistry (IHC) is highly desirable.
• Strong understanding of tissue morphology, histological structures, and pathological changes.
• Ability to independently execute laboratory protocols and troubleshoot technical challenges.
• Strong attention to detail and commitment to generating high‑quality, reproducible data.
• Excellent documentation, communication, organizational, and problem‑solving skills.

Experience / Education

• PhD or advanced degree with 0-2 years of experience

Knowledge / Skills / Abilities

• Proficient in Oral & Written communication skills
• Need to be able to read, write and understand English at proficient level
• Proficient in Microsoft (Excel, Word, Outlook)

Requirements

Physical Requirements:

• Must be able to work in an office environment with minimal noise conditions.
• Must be able to work in Lab setting with exposure to Animals/biohazards / Chemicals (List specific Chemicals)
• Must not have animal allergies to applicable species in this facility
• Must be able to wear appropriate PPE
• Must be able to work in environment with variable noise levels
• Ability to stand /Sit/walk for long periods of time
• Ability to Lift 10 lbs routinely
• Ability to crouch, bend, twist, and reach
• Ability to push/pull 10 lbs routinely/ often / occasionally
• Clarity of Vision
• Ability to identify and distinguish colors
• Must be able to perform activities with repetitive motions
• Ability to climb Ladders / Stairs / Scaffolding
• Ability to work in variable temperatures high to freezing
• Inside/outside working conditions

Anticipated base pay range: $69,036 to $89,570

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job‑related duties as requested by Management.

Your California Privacy Rights