Scientist I

WuXi AppTec; San Diego (CA); On-site; USD 69,036 - 89,570; Full time

Job summary

A leading biopharmaceutical company in San Diego seeks a Scientist I to design and execute complex in vivo pharmacology studies focused on immunology and autoimmune disease models. The ideal candidate will hold a Ph.D. and possess expertise in in vivo procedures, analysis, and report generation. This position offers a base pay range of $69,036 to $89,570, along with a collaborative research environment. Strong emphasis on communication and organizational skills is required.

Qualifications

• Ph.D. degree in a relevant life science field.
• Strong scientific knowledge and experience with rodent handling.
• Experience in in vivo experimental techniques.

Responsibilities

• Design and lead in vivo pharmacology studies.
• Communicate with clients and prepare study reports.
• Oversee operations and ensure regulatory compliance.

Skills

In vivo pharmacology expertise

Scientific writing

Organizational skills

Education

Ph.D. in Immunology, Biology, Pharmacology, or related field

Tools

Flow cytometry

ELISA

Western blot

qPCR

Job description

HD Biosciences Inc. a WuXi AppTec company, offers biology-focused preclinical drug discovery services to biotech and pharmaceuticals. We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, in vivo pharmacology, as well as other research and development services.

We’re seeking highly skilled and motivated Scientist I to design, lead, and execute complex in vivo pharmacology studies focused on immunology and autoimmune disease models, including inflammatory bowel disease (IBD)/colitis models, experimental autoimmune encephalomyelitis (EAE), systemic lupus erythematosus (SLE), and related immune-mediated disease models in immunocompetent and immunocompromised mice.

Responsibilities

Essential Job Functions:

• Provides overall scientific and operational support for in vivo studies.
• Contributes and applies expertise and knowledge to collaborate with partners in the design and execution of related studies.
• Works with business management and development team for sponsor engagement and project proposal preparation.
• Leads multiple ongoing projects to meet expected timelines.
• Responsible for new capability implementation and team building.
• Contributes to the overall operations and to the achievement of departmental goals.
• Communicates with clients for designing, analysis, reporting and recording activities.
• Performs job specific tasks in compliance with applicable Regulations, International Standards, WuXi AppTec Policies and Standard Operating Procedures.
• Hands‑on bench work when necessary.

Qualifications

Experience / Education

• Ph.D. in Immunology, Biology, Pharmacology, or a related life science field.
• Industry experience from CRO or postdoctoral experience preferred; strong scientific knowledge, demonstrated experience in rodent handling and in vivo experimental techniques are highly desired.
• Expert level skills in the following areas are required:
• Perform advanced animal procedures including multiple dosing routes (IV, PO, IP, SC), disease induction, clinical scoring, body weight and symptom monitoring, and collection of blood and tissue samples for downstream analyses.
• Establish, optimize, validate, and troubleshoot in vivo inflammation and autoimmune disease models to support preclinical therapeutic evaluation and mechanism-of-action studies.
• Analyze and interpret experimental data with scientific rigor, generate clear conclusions, and prepare detailed study reports and data summaries for internal teams and external clients.
• Provide technical guidance, training, and study-specific supervision to Research Associates and junior team members while promoting best practices in animal handling and experimental execution.
• Communicate directly with external clients to provide study updates, discuss experimental design, troubleshoot technical issues, and present data interpretations to ensure high-quality scientific delivery.
• Strong organizational and time-management skills with the ability to manage multiple studies simultaneously.
• Excellent scientific writing and verbal communication skills.
• Ability to work effectively in a fast‑paced, collaborative research environment.
• Prior in vitro assays (such as flow cytometry, ELISA, Western blot, qPCR, or similar biomarker analyses) and in vivo pharmacology experience are considered a strong asset.

Knowledge / Skills / Abilities

• Ability to work in a laboratory and vivarium environment with exposure to animals, biohazards, and laboratory chemicals.
• Demonstrated time management and multi-tasking skills, ability to effectively prioritize workload and manage changes in direction.
• Demonstrated ability to lead and manage other scientists and associates.
• Demonstrated ability for attention to details and concern for impact.
• Effective communication skills with the ability to give and receive feedback, both verbally and in writing.
• Ability to work in a team environment and independently as required.
• Ability to work in a fast-paced environment.
• Well organized and adaptable to change.
• Ability to stand, walk, and perform laboratory procedures for extended periods.

Physical Requirements

• Must be able to work in an office environment with minimal noise conditions.
• Must be able to work in a lab setting with exposure to Animals/biohazards/chemicals (List).
• Must not have animal allergies to applicable species in this facility.
• Must be able to work in environment with variable noise levels.
• Ability to stand/sit/walk for long periods of time.
• Ability to lift 10 lbs routinely.
• Ability to push/pull 10 lbs routinely/often/occasionally.
• Clarity of vision.
• Ability to identify and distinguish colors.
• Must be able to perform activities with repetitive motions.
• Ability to climb ladders/stairs/scaffolding.
• Ability to work in variable temperatures high to freezing.
• Inside/outside working conditions.

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Anticipated base pay range: $69,036 to $89,570

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin or protected veteran status and will not be discriminated against on the basis of disability.

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.