Scientist I

Spectraforce Technologies; North Chicago (IL); On-site; USD 65,000 - 90,000; Full time

Job summary

Spectraforce Technologies seeks a Scientist I in North Chicago, IL to perform quantitative LC-MS/MS bioanalysis on synthetic molecules and peptides, analyze data, and document results. The role requires hands-on LC-MS/MS experience, familiarity with ADME/PK/PD concepts, and strong documentation practices in a fast-paced, team-driven environment. Onsite position with standard lab responsibilities.

Qualifications

• Bachelor's degree in a scientific field with 0–3 years of experience, or master's with no experience.
• Experience with quantitative bioanalysis of synthetic molecules and peptides.
• Hands-on with LC-MS/MS platforms and software (Analyst, Discovery Quant, LeadScape, Sciex OS).
• Familiarity with automated sample preparation platforms and ADME/PK/PD concepts.

Responsibilities

• Perform quantitative LC-MS/MS of synthetic molecules and peptides from biomatrices to support ADME bioassays and PK/PD studies.
• Operate, troubleshoot LC-MS/MS instrumentation and perform routine maintenance.
• Maintain documentation of all work in electronic lab notebooks, methods, and protocols.

Skills

Quantitative bioanalysis

LC-MS/MS operation

Data interpretation

Documentation

Team collaboration

Education

Bachelor's degree in chemistry/biology/pharmacology

Tools

Analyst

Discovery Quant

LeadScape

Sciex OS

Electronic Lab Notebook

Job description

Position Title: Scientist I

Work Location: North Chicago, IL 60064

Assignment Duration: 06 Months

Work Arrangement: Onsite (location-based role in North Chicago, IL)

Position Summary:

The Quantitative, Translational, and ADME Sciences Department in North Chicago, IL is seeking a highly motivated team member to operate in an LCMS-based quantitative bioanalytical role to support research and development projects.

The successful candidate will be in a fast-paced, dynamic environment with minimal supervision once trained. The candidate will be responsible for quantitative LC-MS/MS bioanalysis of synthetic molecules and peptides, data analysis and interpretation, and documentation.

Key Responsibilities:

• Perform quantitative LC-MS/MS of synthetic molecules and peptides from in-vitro and in-vivo biomatrices to support ADME bioassays and PK/PD studies.
• Operate and troubleshoot LC-MS/MS instrumentation and perform routine maintenance of LC-MS/MS equipment.
• Maintain excellent documentation of all work, including electronic lab notebooks, methods, and protocols.

Qualifications & Experience:

• Bachelor's degree in a scientific field (e.g., chemistry, biology, pharmacology, or related disciplines), with typically 0-3 years of experience, or a master's degree with no additional experience.
• Experience with quantitative bioanalysis of synthetic molecules and peptides.
• Hands-on experience with one or more current LC-MS/MS platforms (e.g., Sciex triple quadrupoles, Agilent HPLCs, Shimadzu HPLCs, PAL autosamplers, ADDA, LS-II) and software (e.g., Analyst, Discovery Quant, LeadScape, Sciex OS, Electronic Laboratory Notebook).
• Familiarity with automated sample preparation platforms.
• Familiarity with ADME, PK, PD, and bioassays.
• A good understanding of analytical methodologies used for synthetic molecules and peptide quantitation (acquisition, processing, and troubleshooting).
• Ability to work independently or under minimal supervision to conduct experiments, as well as interpret, document, and communicate results.
• Ability to balance generating high-quality data within a standardized, streamlined, and high-throughput environment.
• Ability to work effectively with team members in a dynamic environment, self-motivate, multitask, meet frequent tight deadlines, and adapt to changing priorities.

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