Senior Scientist I, Small Molecule and Peptide Bioanalysis

Allergan; North Chicago (IL); On-site; USD 120,000 - 160,000; Full time

Job summary

AbbVie in North Chicago seeks a scientist to join the Non-regulated Bioanalysis Team. The successful candidate will develop and implement LC/MS-based bioanalysis methods for pipeline-enabling preclinical studies and provide scientific leadership in complex modalities.

Requirements include advanced degrees in analytical chemistry, hands-on LC-MS/MS experience, and mentoring skills. The role emphasizes collaboration, innovation, and keeping current with literature in analytical science.

Qualifications

• PhD (0+ years), MS (8+ years) or BS (10+ years) in analytical chemistry or related field with relevant academic or industry experience.
• In-depth understanding of LCMS methodology and quantitative science, with a focus on synthetic molecules.
• Hands-on experience with LC-MS/MS platforms and software; familiarity with automated sample preparation platforms.
• Knowledge of pharmacokinetics with understanding of experimental design and data analysis will be a plus.
• Working experience in regulated bioanalysis and/or CRO settings will be a plus.
• Proven ability to work in a team environment and an ability to interact with interdisciplinary teams.
• Highly motivated and self-driven with the ability to quickly adapt to shifting priorities.
• Maintain creative and flexible thinking, passionate for learning and solving technical problems
• Excellent communication and presentation skills and the ability to work effectively both independently and as part of team.

Responsibilities

• Support method development and optimization for quantitative bioanalysis, hands-on experience in peptide extraction, separation, and quantification is required.
• Independently investigate, evaluate, and implement new analytical methodologies and technologies to meet challenging assay requirements while maintaining effective resource utilization.
• Identify, troubleshoot, and provide quick response to address instrument and assay issues
• Execute operational activities including supporting pipeline enabling preclinical studies to meet timelines, operate and maintain LC/MS instruments, and maintain accurate study documentation in electronic notebooks.
• Stay current with emerging literature and development of analytical science.
• Mentoring junior scientists.

Skills

LCMS-based bioanalysis

Communication & presentation

Mentoring junior scientists

Team collaboration

Education

PhD in analytical chemistry

MS in analytical chemistry

BS in analytical chemistry

Tools

LC-MS/MS platforms

Automated sample preparation platforms

Job description

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

Purpose

The Quantitative, Translational and ADME Science (QTAS) Department at AbbVie is seeking a highly motivated scientist to join our Non-regulated Bioanalysis Team in North Chicago. In this lab-based role, the ideal candidate will have strong expertise in developing and implementing LC/MS-based bioanalysis to support pipeline enabling preclinical studies, to provide scientific leadership in developing custom methodology for complex modalities, and to evaluate and implement novel technologies and methodologies

Core responsibilities

• Support method development and optimization for quantitative bioanalysis, hands-on experience in peptide extraction, separation, and quantification is required.


• Independently investigate, evaluate, and implement new analytical methodologies and technologies to meet challenging assay requirements while maintaining effective resource utilization.


• Identify, troubleshoot, and provide quick response to address instrument and assay issues


• Execute operational activities including supporting pipeline enabling preclinical studies to meet timelines, operate and maintain LC/MS instruments, and maintain accurate study documentation in electronic notebooks.


• Stay current with emerging literature and development of analytical science.


• Mentoring junior scientists.

Qualifications

• PhD (0+ years), M.S. (8+ years) or BS (10+ years) in analytical chemistry or related field with relevant academic or industry experience.


• In-depth understanding of LCMS methodology and quantitative science, with a focus on synthetic molecules.


• Hands-on experience with one or more current LC-MS/MS platforms and software; familiarity with automated sample preparation platforms.


• Knowledge of pharmacokinetics with an understanding of both experimental design and data analysis will be a plus.


• Working experience in regulated bioanalysis and/or CRO settings will be a plus.


• Proven ability to work in a team environment and an ability to interact with interdisciplinary p


• Highly motivated and self-driven with the ability to quickly adapt to shifting priorities.


• Maintain creative and flexible thinking, passionate for learning and solving technical problems


• Excellent communication and presentation skills and the ability to work effectively both independently and as part of team.

Key Leadership Competencies

• Builds strong relationships with peers and cross functionally with partners outside of the immediate team to enable higher performance.


• Learns fast, grasps the “essence” and can change course quickly when indicated.


• Creates a learning environment, open to suggestions and experiments to drive the science in the field of interest.


• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.


• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.


• This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employer remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html