Scientist, Elitzur Lab

St. Jude Children's Research Hospital; Memphis (TN); On-site; USD 86,000 - 155,000; Full time

Job summary

St. Jude Children's Research Hospital in Memphis seeks a Scientist in the Elitzur Lab to lead investigations into rare hematologic malignancies, spanning pediatric leukemia and lymphoma.

The work emphasizes genomic, transcriptomic, and functional approaches to define disease mechanisms and identify therapeutic vulnerabilities. The candidate will design and execute experiments, analyze large sequencing and clinical datasets, develop patient-derived models, and contribute to manuscripts and grant

Qualifications

• Ph.D. and/or equivalent research experience in cancer biology, genetics, genomics, molecular biology, or a related field
• Demonstrated experience with genomic and/or transcriptomic analysis (e.g., RNA-seq, WES/WGS, single-cell sequencing)
• Experience working with rare disease cohorts, biobanked samples, or multi-institutional data sharing is a strong plus
• Strong analytical and bioinformatics skills, or willingness to collaborate closely with computational biologists
• Track record of scientific productivity (publications, presentations) appropriate to career stage
• Excellent organizational and communication skills, with the ability to manage multiple concurrent projects
• Experience mentoring trainees is desirable

Responsibilities

• Coordinates research projects and performs laboratory experiments; determines tools or methods required
• Sets up protocols and assists in developing new laboratory techniques
• Identifies data pertinent to analysis; processes, summarizes data, and reports results
• May draft sections of research manuscripts
• Maintains lab operations including equipment maintenance, inventory, and calibrations
• Lead and manage projects focused on molecular characterization of hematologic malignancies
• Design and execute experiments using genomic, transcriptomic, and functional approaches
• Integrate and analyze large-scale sequencing and clinical datasets; collaborate with international consortia
• Establish and maintain patient-derived models for rare subtypes
• Contribute to manuscript preparation and grant writing; present findings at conferences
• Maintain records and ensure compliance for human subjects research
• Instructs staff in basic laboratory techniques
• Maintain regular attendance
• Perform other related duties as assigned

Skills

Genomics analysis

Transcriptomics analysis

Bioinformatics

Scientific communication

Education

PhD or equivalent in cancer biology/genomics

Bachelor's degree in relevant science

Tools

RNA-seq

WES

WGS

Single-cell sequencing

Job description

Job Description Summary

The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world‑class facilities. State‑of‑the‑art technologies. Extraordinary support. And a collaborative, bench‑to‑bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children.

Thel aboratory of Dr. Sarah Elitzur in the Department of Oncology , St. Jude Children's Research Hospital, is seeking a r esearch s cientist to lead investigations into rare and understudied subgroups of hematologic malignancies. Our lab is focused on characterizing the genomic, molecular, and clinical features of uncommon hematologic mal i gnancy subtypes, with the goal of defining novel biological mechanisms and identifying therapeutic vulnerabilities for patient populations that remain underrepresented in mainstream research. This is an excellent opportunity for a scientist interested in working at the intersection of rare disease biology, precision medicine, and translational hematology‑oncology.

The successful candidate will perform and coordinate a wide range of laboratory research procedures and conduct complex research projects within the field of pediatric leukemia and lymphoma. This role requires the ability to perform a variety of advanced laboratory techniques independently, analyze and interpret experimental data, and present research findings. The individual will contribute to ongoing research initiatives while supporting the development of new experimental approaches and technologies that advance the laboratory's scientific goals.

Job Responsibilities

• Coordinates multiple aspects of research projects and carries out laboratory experiments utilizing various laboratory techniques, and determines whether additional or other tools or methods are required

• Provides input regarding research protocols and experiments. Sets up protocols and assists in developing new laboratory techniques as required .

• Identifies experimental data pertinent to the analysis problem. Processes, organizes and summarizes data, reporting these experimental results as required . Monitors quality and integrity of recorded information and data

• May draft sections of research manuscripts.

• Provides basic lab operation support to include equipment maintenance and purchasing . Monitors inventory levels and orders lab supplies as needed. Performs calibration of instruments and equipment. Troubleshoots instrument performance and equipment issues.

• Lead and manage research projects focused on the molecular characterization of hematologic malignancy s

• Design and execute experiments using genomic, transcriptomic, and functional approaches to define disease mechanisms

• Integrate and analyze large-scale sequencing and clinical datasets, including collaboration with international consortia when relevant

• Establish and maintain patient-derived models representing rare disease subtypes

• Contribute to manuscript preparation, grant writing, and presentation of findings at scientific conferences

• Maintain meticulous records and ensure regulatory compliance for human subjects research

• Instructs other staff in basic laboratory techniques and procedures.

• Maintains regular and predictable attendance

• Performs other related duties as assigned in order to meet the goals of the department and institution

Preferred Qualifications

• Ph.D. and/or equivalent research experience in cancer biology, genetics, genomics, molecular biology, or a related field

• Demonstrated experience with genomic and/or transcriptomic analysis (e.g., RNA-seq, WES/WGS, single-cell sequencing)

• Experience working with rare disease cohorts, biobanked samples, or multi-institutional data sharing is a strong plus

• Strong analytical and bioinformatics skills, or willingness to collaborate closely with computational biologists

• Track record of scientific productivity (publications, presentations) appropriate to career stage

• Excellent organizational and communication skills, with the ability to manage multiple concurrent projects

• Experience mentoring trainees is desirable

Minimum Education and/or Training

• Bachelor's degree in relevant scientific area is required .

Minimum Experience

• Eight (8) years of relevant work experience is required

• Six (6) years of relevant work experience is required with a Master's degree

• Three (3) years of relevant work experience is required with a PhD

Compensation

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist, Elitzur Lab.

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St. Jude is an Equal Opportunity Employer