Lead Researcher - Dyer Lab

St Jude Children's Research Hospital; Memphis (TN); On-site; USD 60,000 - 105,000; Full time

Job summary

St. Jude Children's Research Hospital in Memphis seeks a motivated Lead Researcher to study molecular and cellular mechanisms of development and disease, integrating developmental biology, cancer biology, and translational science.

The successful candidate will use molecular, biochemical, and cell biology approaches, with opportunities for growth in human stem cell and tumor organoid culture, advancing translational research for pediatric cancer.

Qualifications

• Bachelor's degree in a relevant scientific area is required.
• 5+ years of research experience is required.
• 3+ years of experience with a Master's degree; PhD holders may have different experience.
• Strong knowledge of molecular biology techniques and lab practices.

Responsibilities

• Develop and perform procedures using established or modified techniques/protocols
• Implement new but established protocols without individual training
• Troubleshoot experiments and identify anomalies in own data
• Consistently monitors current literature and trends within field
• Accurately record experimental procedures and data
• Prepare and report results/ data leading to posters, presentations, or publications
• Provide guidance to less-experienced team members
• Perform other duties as assigned to meet the goals and objectives of the department and the institution.
• Maintain regular and predictable attendance.

Skills

Molecular biology

PCR/qPCR

Cell culture

DNA/RNA isolation

Data analysis

Education

Bachelor's degree in a relevant scientific field

Job description

We are seeking a motivated, detail-oriented Lead Researcher to study the molecular and cellular mechanisms underlying development and disease. Our research integrates developmental biology, cancer biology, and translational science to investigate how gene regulatory networks and cellular processes control tissue development and homeostasis, and how their disruption drives disease. Current projects include retinal aging and disease, super-enhancer biology, intratumoral heterogeneity, and advanced tumor model development, aimed at identifying novel therapeutic targets and advancing treatments for children with cancer.

The successful candidate will utilize a variety of molecular, biochemical, and cell biology approaches to support these research programs and generate data that advance our understanding of developmental and disease mechanisms. This position requires the ability to work with some independence on assigned responsibilities while collaborating effectively with investigators, scientists, and research team members in a highly interactive research environment. The ideal candidate will have moderate proficiency in common molecular biology and biochemical assays, including techniques such as DNA/RNA isolation, PCR/qPCR, protein detection assays, and cell-based assays. This role also offers exciting opportunities for professional growth through training and participation in cutting-edge human stem cell and tumor organoid culture research, providing exposure to next generation in vitro model systems and translational research applications.

Job Responsibilities:

• Develop and perform procedures using established or modified techniques/protocols
• Implement new but established protocols without individual training
• Troubleshoot experiments and identify anomalies in own data
• Consistently monitors current literature and trends within field
• Accurately record experimental procedures and data
• Prepare and report results/ data leading to posters, presentations, or publications
• Provide guidance to less-experienced team members
• Perform other duties as assigned to meet the goals and objectives of the department and the institution.
• Maintain regular and predictable attendance.

Minimum Education and/or Training:

• Bachelor's degree in a relevant scientific area is required

Minimum Experience:

• 5+ years of research experience is required
• 3+ years of experience is required with a Master's degree
• No prior experience required with a PHD
• Strong knowledge and experience in understanding and application of underlying principles related to techniques being performed
• Experience in R&D methods and processes in lab setting, and execution of research projects for the laboratory preferred
• Proven performance in earlier role/comparable role.

Compensation

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $60,320 - $105,040 per year for the role of Lead Researcher - Dyer Lab.

St. Jude is an Equal Opportunity Employer