Scientist- CHO Cell Line Development

Integrated Resources, Inc ( IRI )

Foster City (CA)

On-site

USD 110,000 - 170,000

Full time

15 hours ago
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Job summary

Integrated Resources, Inc (IRI) seeks a dedicated Cell Line Development specialist to execute experiments supporting our rapidly growing biologics pipeline. Responsibilities include mammalian culture, cloning, cell banking, and routine maintenance to advance pipeline programs.

The role emphasizes applying automation and high-throughput methods for CHO line generation, data analysis, and clear reporting. Collaboration with multiple teams ensures timelines are met in a fast-paced environment.

Qualifications

  • Bachelor's degree with 6+ years or Master's with 4+ years in biotech, with substantial mammalian CLD experience.
  • Hands-on CHO cell line development experience including culture, transfection, cloning, cell banking, and shake-flask operations.
  • Experience supporting CLD programs in biopharma; Scientist-level experience preferred.

Responsibilities

  • Execute end-to-end CLD activities including mammalian culture, transfection, cloning, screening, banking, and production.
  • Independently perform experiments, analyze data, troubleshoot issues, and document results.
  • Collaborate with Cell Line Development and cross-functional teams to meet project timelines.

Skills

CHO cell line development
Mammalian cell culture
Transfection
Single-cell cloning
Clone screening
Cell banking
Cell counting
Shake-flask operations
Bench-scale bioreactors
Automated liquid handling
High-throughput screening
Data analysis
Technical report writing
Cross-functional collaboration
Project timeliness management

Education

Bachelor's degree with 6+ years in biotechnology or related field
Master's degree with 4+ years in biotechnology or related field

Tools

Bench-scale bioreactors
Automated liquid handling systems
High-throughput screening technologies

Job description

Client has an opportunity in the Cell Line Development (CLD) group We are seeking a highly motivated, team-oriented individual to execute experiments to support cell line development for our rapidly growing biologics pipeline.

Responsibilities
  • Execute end-to-end Cell Line Development (CLD) activities in support of pipeline programs, including mammalian cell culture, transfection, single-cell cloning, clone screening, cell banking, fed-batch production, and routine cell line maintenance.
  • Independently perform laboratory experiments, analyze data, troubleshoot technical challenges, and document results in a timely and organized manner.
  • Support and apply automation and high-throughput technologies to enhance CHO cell line generation, clone selection, and workflow efficiency.
  • Collaborate closely with Cell Line Development team members and cross-functional partners, including Cell Culture, Analytical Development, and Pilot Plant teams, to achieve project objectives and timelines.
  • Contribute to technical reports, presentations, and project discussions, effectively communicating experimental outcomes and recommendations.
Skills & Qualifications
  • Bachelor's+6 years or Master's+4 years degree in Biotechnology, Biochemical Engineering, Biological Sciences, or a related field, with substantial industry experience in mammalian Cell Line Development.
  • Strong hands-on experience in CHO cell line development, including cell culture, transfection, single-cell cloning, clone screening, cell banking, cell counting, and shake-flask operations.
  • Demonstrated experience supporting cell line development programs in a biopharmaceutical or biotechnology environment; prior experience performing duties comparable to a Scientist-level role is strongly preferred.
  • Experience with bench-scale bioreactors, automated liquid handling systems, and/or high-throughput screening technologies is preferred.
  • Strong understanding of cell line development workflows, experimental design, data analysis, and troubleshooting.
  • Excellent written and verbal communication skills, including technical report writing and presentation of scientific data.
  • Proven ability to work independently while effectively collaborating in a fast-paced, cross-functional team environment.
  • Highly organized, detail-oriented, and able to manage multiple priorities while meeting project timelines.
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