Scientist, Bioanalytical

Merck; Illinois; On-site; USD 108,000 - 170,000; Full time

Job summary

Merck's Research Laboratories seeks a bioanalytical scientist to support preclinical drug discovery in the DMPK group. The role involves conducting in vitro and ex vivo studies on novel drug candidates across multiple modalities, with emphasis on characterizing drug disposition and pharmacology to inform pipeline decisions.

Responsibilities include planning studies, interpreting data for pipelines, advancing ADME science, and collaborating with cross-functional teams on candidate

Qualifications

• 3+ years experience with analytical sciences or related discipline.
• Hands-on cell culture and cell-based assays.
• Experience in biologics bioanalytical experimentation and ligand binding assays.

Responsibilities

• Plan and conduct in vitro/ex vivo studies to characterize DMPK properties.
• Interpret data and present results to multidisciplinary teams.
• Contribute to understanding ADME and discovery bioanalytical science.
• Collaborate with cross-functional teams on novel candidates.

Skills

Cell culture

Cell-based assays

Biologics bioanalytical

Data analysis

Communication

Collaborative work

Education

Bachelor's degree + 3+ years experience

Master's degree

Tools

GraphPad

Excel

Job description

Merck's Research Laboratories seeks a bioanalytical scientist to support preclinical drug discovery in the DMPK group. The role involves conducting in vitro and ex vivo studies on novel drug candidates across multiple modalities, with emphasis on characterizing drug disposition and pharmacology to inform pipeline decisions.

Responsibilities

• Plan and conduct in vitro/ex vivo studies to characterize DMPK properties of biologics and conjugates
• Interpret experimental data and present results to multidisciplinary teams for pipeline decision-making
• Contribute to scientific initiatives advancing understanding of ADME and discovery bioanalytical science
• Collaborate with cross-functional teams on characterization of novel drug candidates across therapeutic areas

Requirements

• Bachelor's degree with 3+ years experience or Master's in analytical science, biology, biochemistry, pharmaceutical sciences, or related discipline
• Hands-on experience with mammalian cell culture and cell-based assays
• Demonstrated experience in biologics bioanalytical experimentation including ligand binding assays and FACS
• Proficiency with data analysis software such as GraphPad or Excel
• Excellent scientific, interpersonal, and communication skills
• Ability to work collaboratively in fast-paced research environments

Compensation: $108,000–$170,100 base