DMPK Bioanalytical Scientist (In Vitro/Ex Vivo)

Merck; Grand Junction (CO); On-site; USD 108,000 - 170,000; Full time

Job summary

Merck's Research Laboratories seeks a bioanalytical scientist to support preclinical drug discovery in the DMPK group. The role involves conducting in vitro and ex vivo studies on novel drug candidates across multiple modalities, with emphasis on characterizing drug disposition and pharmacology to inform pipeline decisions.

The candidate will plan and conduct DMPK studies, interpret data for multidisciplinary teams, and contribute to advancing understanding of ADME and discovery bioanalytical

Qualifications

• Bachelor's degree with 3+ years experience or Master's in analytical sciences or related field.
• Experience with mammalian cell culture and cell-based assays.
• Experience in biologics bioanalytical testing including ligand binding assays and FACS.

Responsibilities

• Plan and conduct in vitro/ex vivo studies to characterize DMPK properties of biologics and conjugates.
• Interpret experimental data and present results to multidisciplinary teams for pipeline decision-making.
• Contribute to scientific initiatives advancing understanding of ADME and discovery bioanalytical science.
• Collaborate with cross-functional teams on characterization of novel drug candidates across therapeutic areas

Skills

Mammalian cell culture

Cell-based assays

Ligand binding assays

FACS

Data analysis with GraphPad/Excel

Collaborative, team-oriented

Education

Bachelor's degree with 3+ years or Master's in analytical science/biology/biochemistry/pharmaceutical sciences

Tools

GraphPad

Excel

Job description

Merck's Research Laboratories seeks a bioanalytical scientist to support preclinical drug discovery in the DMPK group. The role involves conducting in vitro and ex vivo studies on novel drug candidates across multiple modalities, with emphasis on characterizing drug disposition and pharmacology to inform pipeline decisions.

The candidate will plan and conduct DMPK studies, interpret data for multidisciplinary teams, and contribute to advancing understanding of ADME and discovery bioanalytical