Scientist, Antibody Developability

Kelly

San Francisco (CA)

On-site

USD 90,000 - 110,000

Full time

6 days ago
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Benefits offered by this job

15 days PTO
Health benefits
Kelly-sponsored plans
HSA or FSA
401K retirement (no match)
Major holidays

Job summary

Kelly Science & Clinical is seeking a Scientist, Antibody Developability for a fully benefitted 12-month contract in the San Francisco Bay Area. The role focuses on designing dose solution studies and advancing AI-driven drug candidates toward IND-ready status.

You will develop ultra-sensitive protein characterization methods and drive formulation screening, while collaborating with CROs and internal teams to accelerate progress and deliver robust data.

Qualifications

  • PhD in Biochemistry or related discipline required.
  • 5+ years hands-on biotech bench experience.
  • Proven ability to develop and optimize chromatography-based assays and methods.

Responsibilities

  • Design and execute in-use dose solution studies for drug candidates and materials.
  • Develop ultra-sensitive protein characterization methods and quality assessment metrics.
  • Drive formulation screening, stress testing, and peptide mapping for top leads.
  • Assess purity, stability, tolerability, and biophysical properties across programs with data interpretation.
  • Collaborate with external CROs to ensure high-quality testing and analytics.
  • Communicate complex findings and propose next steps to multidisciplinary teams.
  • Scout, validate, and apply new analytical tools and developability technologies.

Skills

Chromatography assays
Biophysical analysis
Antibody characterization
Data interpretation

Education

PhD in Biochemistry or related

Tools

Laboratory automation
High-throughput workflows

Job description

Kelly® Science & Clinical is seeking a Scientist, Antibody Developability for a fully benefited contract-to-hire opportunity with a biotechnology client in the Bay Area that is developing the next generation of antibody therapeutics. If you are driven by the prospect of translating cutting-edge scientific discoveries into tangible advancements and are poised to advance your career, join us as we pioneer progress in the biotechnology and medical device industries.

Workplace: Onsite in the San Francisco, Bay Area

Position Title: Scientist, Antibody Developability

Position Type: Fully benefitted 12-month contract

Pay rate: $65-80 per hour

  • 15 Days PTO
  • Health benefits include individual and dependents
  • Options include Kelly-sponsored plans
  • Options for HSA or FSA
  • Merrill Lynch retirement program (401K, Roth, no match)
  • Major holidays and any client-specific holidays
Overview

Join our client, a trailblazer in AI-driven drug discovery, and transform the landscape of protein therapeutics! We’re seeking a creative and highly skilled bench scientist who thrives in fast-paced environments and is passionate about advancing late-stage AI-designed therapeutics from their innovative platform to IND-ready stage.

What You'll Do:
  • Lead the Charge: Design and execute in-use dose solution studies, ensuring seamless compatibility of cutting-edge drug candidates with administration materials.
  • Innovate at the Bench: Develop novel, ultra-sensitive protein characterization methods (qSEC, RP-HPLC, CEX, particle counting, etc.) that set industry standards for quality assessment and recovery.
  • Advance Drug Candidates: Drive formulation screening, rigorous stress testing, and illuminating peptide mapping to identify and elevate top leads for further clinical development.
  • Champion Developability: Assess and optimize purity, stability, tolerability, and biophysical properties across multiple programs, with meticulous data interpretation and documentation to fuel accelerated progress.
  • Collaborate for Impact: Partner and oversee external CROs, ensuring world-class testing and analytics for our industry-leading therapeutics pipeline.
  • Amplify Your Findings: Distill and communicate complex scientific discoveries, propose strategic next steps, and broadcast insights across multidisciplinary teams.
  • Discover & Deploy New Tech: Stay ahead of the curve by scouting, validating, and implementing state-of-the-art analytical tools and developability technologies that set new industry benchmarks.
Who You Are:
  • Academic & Industry Visionary: PhD in Biochemistry or related discipline, with 5+ years of hands-on biotech expertise. Exceptional non-PhD candidates with deep bench experience are encouraged to apply.
  • Analytical Mastermind: Proven excellence in developing and optimizing chromatography-based assays and methods.
  • Protein Characterization Expert: Extensive experience with biophysical and analytical evaluation of antibodies and fragments, SEC, HIC, CE-SDS, DLS, DSF, ELISA, LC-MS, and more.
  • Data-Driven Communicator: Track record of converting complex data into actionable insights that drive results and innovation.
  • Technology Trailblazer: Eager to rapidly learn, adopt, and deploy next-gen technologies that boost output, efficiency, quality, and cost-effectiveness.
Bonus Points For:
  • Experience thriving in a dynamic startup environment
  • Leadership as a project owner/manager
  • Expertise with laboratory automation and high-throughput workflow
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