Scientist, Analytical Sciences

AstraZeneca; Santa Monica (CA); On-site; USD 87,000 - 131,000; Full time

Job summary

A leading company in Santa Monica is seeking a passionate Scientist for their Analytical Sciences team. This role involves defining critical quality attributes, optimizing flow cytometry, and collaborating on regulatory filings. Ideal candidates will have a strong background in immunology or cell biology, with hands-on experience in flow cytometry and cell culture. Join a dynamic team committed to advancing cell therapy solutions.

Benefits

401(k) plan

Paid vacation

Health benefits

Qualifications

• 3 years with BS/BA or 2 years with MS/MA in relevant field.
• Extensive hands-on experience with multiparameter flow cytometry.
• Experience in developing and executing cytotoxicity assays.

Responsibilities

• Design and optimize flow cytometry panels for cell therapy products.
• Collaborate with Process Development to define product attributes.
• Contribute to regulatory filings through high-quality data packages.

Skills

Flow Cytometry

Cell Culture

Data Analysis

Critical Thinking

Education

BS/BA in Immunology

MS/MA in Cell Biology

Tools

FlowJo

GraphPad Prism

R

Python

Job description

Join to apply for the Scientist, Analytical Sciences role at AstraZeneca

Join to apply for the Scientist, Analytical Sciences role at AstraZeneca

We are looking for a passionate and technically experienced Scientist to join our Attribute Sciences team. This role is important for defining critical quality attributes (CQAs), supporting analytical development, and informing process and product understanding across all stages of development. You will have hands-on experience in flow cytometry and aseptic cell culture. This on-site role is based in Santa Monica, CA, and reports to the Associate Director, Attribute Sciences.

You Will:

• Design, develop, and optimize flow cytometry panels for deep phenotypic and functional characterization of cell therapy products.
• Execute and analyze cell-based cytotoxicity/killing assays (e.g., Luciferase, IncuCyte, or flow-based assays) to assess product potency.
• Collaborate closely with Process Development and Manufacturing teams to define the relationship between process parameters and product attributes.
• Analyze complex datasets using advanced analytical tools; interpret results to drive scientific conclusions and inform CQA strategy.
• Contribute to regulatory filings (e.g., IND, BLA) through the generation of high-quality data packages and technical documentation.
• Stay up-to-date on emerging technologies and industry trends in analytical development and cell therapy.
  
  
  

You Have:

• Three (3) years with BS/BA, or two (2) years with MS/MA in immunology, Cell Biology, Oncology, Molecular Biology, or a related discipline with experience in a biotechnology, biopharmaceutical, or academic setting.
• Extensive hands-on experience with multiparameter flow cytometry, including panel design, assay development, and data interpretation.
• Extensive mammalian cell culture experience, utilizing aseptic methods and procedures.
• Proficiency with analysis tools such as FlowJo and GraphPad Prism; scripting experience (e.g. R Python) is a plus.
• Ability to work independently and in cross-functional teams.
• Strong trouble shooting and critical thinking skills.
• Attention to details and following good documentation practices.
• Familiarity with analytical development in a regulated environment, including assay qualification and method lifecycle management.
• Experience in developing and executing cell killing or cytotoxicity assays for potency assessment.
• Understanding of quality by design (QbD) principles and regulatory expectations for cell therapies a plus.
  
  
  

The annual base salary for this position ranges from $87,200 to 130,800. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).

Our Benefits:

• A qualified retirement program [401(k) plan]
• Paid vacation, holidays, and paid leaves
• Health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.
  
  
  

#celltherapy

Seniority level

• Seniority level

  Entry level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Pharmaceutical Manufacturing

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