Scientist - Analytical Chemistry

BioSpace; South San Francisco (CA); On-site; USD 125,000 - 150,000; Full time

Job summary

BioSpace is seeking a Scientist in Analytical Chemistry to support gene therapy drug development. The position requires extensive expertise in mass spectrometry and chromatography, emphasizing creativity and teamwork. Ideal candidates should thrive in a start-up environment and possess strong analytical skills to contribute effectively to the team.

Benefits

Equity and ownership

Access to a 24-hour gym

Comprehensive medical, dental, and vision

Commuting stipend

401(k) Match

Flexible time off policy

Qualifications

• Ph.D. with 2+ years experience or M.S. with 6+ years in relevant fields.
• Strong record-keeping and organizational skills required.
• Ability to thrive in a fast-paced, start-up environment.

Responsibilities

• Develop assays in support of gene therapy programs.
• Analyze proteomics data using specialized software.
• Work within interdisciplinary teams to achieve project goals.

Skills

Mass Spectrometry

Chromatography

Analytical Assays Development

Problem Solving

Communication

Education

Ph.D. in Analytical Chemistry or related field

M.S. with industry experience

Tools

LC-MS

HPLC

Skyline

Job description

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Location: South San Francisco, CA

Status: Regular Full-Time

Reports To: Associate Director, Gene Therapy

About SonoThera

SonoThera is a venture capital-backed early-stage biopharmaceutical company developing ultra-sound-guided non-viral targeted gene therapies to treat multiple diseases of high unmet need. The Gene Therapy group at SonoThera uses a collaborative, interdisciplinary, and forward-thinking approach to solving many of the current challenges facing genetic medicine discovery and drug development. SonoThera is headquartered in South San Francisco, CA.

Job Summary

The Gene Therapy group at SonoThera is seeking to hire a Scientist to become an integral part of the gene therapy drug development effort. We seek candidates who think critically and have the desire and ability to learn new techniques. This position requires adaptability and an ability to perform at a high level in a fast-paced environment. The ideal candidate will leverage their mass spectrometry and chromatography expertise to develop assays in support of SonoThera’s gene therapy programs.

Qualifications

• Ph.D. with 2+ years or M.S. with 6+ years of industry experience in analytical chemistry, chemical biology, biochemistry or a related field.
• Creativity and the ability to work within an interdisciplinary team to achieve technical and corporate milestones.
• Ability to thrive in a fast-paced, start-up environment.
• Strong verbal and written communication, critical thinking, and problem-solving skills.
  
  
  

Technical Requirements And Skills

• Extensive expertise in the development of analytical assays to support drug product characterization, including LC/UV, LC/MS, CE, and biochemical readouts.
• Successful development of proteomic and metabolic assays is preferred.
• Knowledge of purification with different chromatography methods including HPLC, IEX, and SEC for protein conjugations.
• Previous experience using state-of-the-art LC-MS equipment for MRM/SRM and TOF analysis (Shimadzu,Agilent, Waters, ExionLC AE, Sciex).
• Analyze proteomics data using proteomics analysis software (Skyline) and bioinformatics tools for protein and peptide quantification.
• Working knowledge with recombinant protein downstream purification and characterization.
• Research literature and external sources and identify new techniques and procedures.
• Ideal candidate will have familiarity with ELNs (i.e. Benchling), Olink-based proteomics, MSD, Western blot, metabolomics and unbiased proteomics analysis.
• Strong record-keeping and organizational skills.
  
  
  

Compensation: The salary range for this position is $125,000.00 to $150,000.00 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.

Benefits

At SonoThera, we'll give you the tools to feel healthy, happy and secure.

Equity and ownership in a fast-growing company.

Access to a 24-hour gym

Comprehensive medical, dental, and vision

Commuting stipend based on your geographical location

401(k) Match: SonoThera offers a dollar-for-dollar match

All full-time employees are eligible for our flexible time off policy

Equal Opportunity for Diversity & Inclusion

SonoThera provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

We do not accept unsolicited agency resumes.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Internet News

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