Scientist

SPECTRAFORCE; Worcester (MA); On-site; USD 70,000 - 100,000; Full time

Job summary

A leading company in the biotechnology sector is seeking a highly motivated Scientist to join their AAV Technologies team. The role involves hands-on laboratory work focusing on chromatographic protein purification and optimizing methods for rAAV pipeline advancements. The successful candidate will work in a fast-paced environment, contribute to scientific publications, and mentor others in new techniques. Ideal candidates will have a strong educational background in science and relevant experience in protein purification and chromatography methods.

Qualifications

• 5+ years experience or PhD with no experience necessary.
• Experience in protein purification and chromatography.
• Demonstrated scientific writing and communication skills.

Responsibilities

• Purification of rAAV to support discovery research.
• Develop and optimize production of high-quality AAV preps.
• Analyze experimental data and maintain Electronic Lab Notebook.

Skills

Protein purification

Scientific writing

Communication

Multitasking

Chromatography methods

Education

BS or equivalent education

MS or equivalent education

PhD

Tools

AKTA FPLC systems

Ion exchange chromatography

Ultracentrifugation

Job description

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The Genetic Medicine Group is seeking a highly motivated and experienced Scientist to join our AAV Technologies team and work collaboratively with our therapeutic area teams to advance company’s rAAV pipeline. The successful candidate will have experience in chromatographic protein purification. The candidate will work in a fast-paced environment to investigate, develop, and optimize methods and technologies through hands-on laboratory work and literature review.

Key Responsibilities Include:

· Purification of rAAV to support discovery research

· Develop and optimize production of high concentration and high quality AAV preps

· Analyze experimental data, generate plots, and summarize results and conclusions.

· Maintain a comprehensive Electronic Lab Notebook documenting experiments.

· Independently design, execute, and interpret critical experiments to answer scientific questions

· Understand the broad objectives of the project as well as their role in achieving those objectives, and modify experimental plan when required, to respond.

· Innovate and implement new experimental protocols.

· Demonstrate a high level of proficiency.

· Set and meet experimental timelines. Impact projects mostly through lab activities.

· Learn, understand, and master new experimental techniques, and act as a resource of mentor for others.

· Routinely read and apply relevant scientific literature. Contribute to writing and conceptual framework of publications, presentations, and patents. Effectively organize and present scientific plans and data.

· Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials in a BSL2 environment.

Qualifications:

· BS or equivalent education with typically 5 or more years of experience, or MS or equivalent education with typically 5 or more years of experience, or PhD and no experience necessary

· Protein purification experience with AKTA FPLC systems and chromatography methods.

· Demonstrated ability to learn, understand, and master new experimental techniques.

· Ability to multitask and work within timelines.

· Demonstrated scientific writing skills and strong verbal communication skills.

Preferred Qualifications:

· Immuno Affinity Purification of multiple rAAV serotypes

· Empty/Full Capsid Separation via ion exchange chromatography and ultracentrifugation

What are the top 3-5 skills, experience or education required for this position?

1. BS with 5 + years of experience, or MS or equivalent education with 5 + years of experience, or PhD and no experience necessary

2. Protein purification experience with AKTA FPLC systems and chromatography methods.

3. Immuno Affinity Purification of multiple rAAV serotypes

4. Empty/Full Capsid Separation via ion exchange chromatography and ultracentrifugation

5. (3 and 4 are preferred but not required)

· Candidates with BS and 3-5 years of experience will be considered for Scientist I

Type of interview (video, phone or onsite)?

1st Round: 30 min video with manager 2nd Round: 3 hour onsite or virtual Ø 30 min presentation plus 15min Q&A, then have 4 x 30 minute 2-3 on 1 meetings and a final 15 minute meeting with manager

Seniority level

• Seniority level

  Associate

Employment type

• Employment type

  Contract

Job function

• Job function

  Science, Research, and Manufacturing

• Industries

  Pharmaceutical Manufacturing, Biotechnology Research, and Manufacturing

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