Scientist

Collabera Inc.; South San Francisco, Northern (CA, KY); Hybrid; USD 130,000 - 180,000; Full time

Benefits offered by this job

medical insurance

dental insurance

vision insurance

401(k) retirement plan

life insurance

long-term disability insurance

short-term disability insurance

paid parking/public transportation

paid time off and sick time and paid休?

Job summary

Collabera Inc. in South San Francisco, CA, seeks a Scientist II to support biologics drug discovery and engineering in a dynamic enterprise environment.

You will design and execute in vitro display technologies to identify and optimize lead antibodies, and contribute to data packages for proof-of-concept activities. The role requires strong molecular and cell biology skills, experience with binding assays (ELISA, flow cytometry, SPR), and familiarity with antibody engineering, library design,

Qualifications

• BS or MS in Biology or related field with 5+ years' relevant experience.
• Hands-on experience with in vitro antibody discovery display technologies (phage/yeast).
• Direct experience with binding assays (ELISA, flow cytometry, SPR).
• Strong molecular and cell biology skills including cloning, sequence analysis, cultured cells.
• Familiarity with protein structure, antibody affinity, and fragments.

Responsibilities

• Design and execute in vitro antibody discovery display technologies to support lead identification and optimization.
• Perform binding assays including ELISA, flow cytometry, and surface plasmon resonance.
• Apply molecular and cell biology techniques including cloning, sequence analysis, bacterial/yeast culture, and mammalian culture.
• Support antibody engineering and optimization activities including affinity modulation and humanization.
• Collaborate with research teams to generate in vitro and in vivo data packages for proof of concept.
• Analyze results and document and communicate scientific findings.
• Present research findings and conclusions in group settings.

Skills

Molecular biology

Cell biology

Antibody discovery

Data analysis

Scientific communication

Education

BS or MS in Biology or related field

Tools

Prism

Geneious

Genedata

Job description

Contract Duration: 12 months with possible extension

Job Summary:

• The Scientist II will support biologics drug discovery and engineering within a dynamic large enterprise environment.
• The role will focus on the design and execution of in vitro display technologies for lead antibody identification and optimization.
• The scientist will contribute to the generation of in vitro and in vivo data packages supporting proof of concept activities.
• The position requires strong expertise in molecular biology, cell biology, antibody discovery, binding assays, and protein engineering concepts.
• The successful candidate will analyze, document, and communicate experimental data while collaborating effectively with cross functional research teams.

Key Responsibilities:

• Design and execute in vitro antibody discovery display technologies to support lead identification and optimization.
• Perform binding assays including ELISA, flow cytometry, and surface plasmon resonance.
• Apply molecular and cell biology techniques including molecular cloning, sequence analysis, bacterial culture, yeast culture, and mammalian cell culture.
• Support antibody engineering and optimization activities including affinity modulation, humanization, and liability engineering.
• Collaborate with research teams to generate in vitro and in vivo data packages supporting proof of concept activities.
• Analyze experimental results and effectively document and communicate scientific findings.
• Present research findings and scientific conclusions in group settings.

Required Qualifications:

• Bachelor of Science or Master of Science degree in Biology or a related scientific field.
• Typically 5 or more years of relevant experience with a Bachelor of Science degree or 2 or more years of relevant experience with a Master of Science degree.
• Hands on experience with in vitro antibody discovery display technologies such as phage display or yeast display.
• Direct experience with binding assays such as ELISA, flow cytometry, or surface plasmon resonance.
• Strong molecular and cell biology skills including molecular cloning, sequence analysis, bacterial or yeast culture, and mammalian cell culture.
• Familiarity with protein structure, antibody affinity, antibodies, and antibody fragments.
• Strong data analysis, documentation, written communication, and presentation skills.

Preferred Qualifications:

• Experience with antibody engineering and optimization including affinity modulation, liability engineering, and humanization.
• Experience with antibody library design and construction.
• Experience with mammalian cell culture and multiplex flow cytometry.
• Experience with automation of biologics discovery processes.
• Proficiency with Prism, Geneious, or Genedata.
• Proficiency with MS Office Suite including Excel, PowerPoint, and Word.

Benefits

The Company offers the following benefits for this position, subject to applicable eligibility requirements:

• medical insurance
• dental insurance
• vision insurance
• 401(k) retirement plan
• life insurance
• long-term disability insurance
• short-term disability insurance
• paid parking/public transportation
• (paid time , paid sick and safe time , hours of paid vacation time, weeks of paid parental leave, paid holidays annually - AS Applicable)