Scientist

Spectraforce Technologies; Cambridge (MA); On-site; USD 70,000 - 100,000; Full time

Job summary

A leading company in biotherapeutics is seeking a Contract Scientist to support their siRNA group. This role involves leading cutting-edge experimental approaches in RNA-based therapies and requires a PhD in relevant fields. Ideal candidates will demonstrate strong hands-on abilities in molecular biology and excellent collaborative skills.

Qualifications

• PhD or MS degree in molecular biology, cell biology, neuroscience, or biochemistry.
• Significant hands-on experience in cell and molecular biology, including mammalian cell culture.
• Familiarity with RNA extraction, qPCR, protein quantification (ELISA and Western).

Responsibilities

• Lead research efforts within a cross-functional team for siRNA platform development.
• Perform laboratory research independently, ensuring high-quality results.
• Analyze and interpret data, generating conclusions that drive future directions.

Skills

Hands-on experience in cell and molecular biology

Collaborative team player

Excellent communication skills

Ability to thrive in a fast-paced environment

Creative problem solving

Education

PhD in Cell Biology, Molecular Biology, Biochemistry

Master's degree with 8 years experience

Tools

qPCR

ELISA

Western blot

Job description

Job Title: Scientist

Location: Cambridge, MA, 02138

Duration: 12 months



Position Overview:

Seeking a Contract Scientist to support the siRNA group within the Biotherapeutics and Genetic Medicine (BGM) department. This temporary position offers the opportunity to contribute to the design and execution of cutting-edge experimental approaches to address key scientific challenges related to oligonucleotide therapeutics. The successful candidate will apply their scientific expertise to drive innovation, collaborate across teams, and support the development of novel RNA-based therapies.



Responsibilities:

* Lead research efforts within a cross-functional team to advance siRNA platform development for therapeutic applications.

* Resolve key project hurdles and assumptions utilizing available information and technical expertise

* Work autonomously to perform laboratory research or develop methods with minimal supervision, consistently delivering high-quality results.

* Demonstrate expertise in a wide range of relevant technologies and methodologies.

* Conceive and execute novel scientific research that achieves project goals

* Maintain high productivity in the laboratory, ensuring efficiency in experiment execution.

* Analyze and interpret multidisciplinary data, generating conclusions that drive future experimental directions.

* Contribute to internal reports, presentations, and potentially intellectual property filings.



Skills and Requirements:

* PhD (or equivalent experience) in Cell Biology, Molecular Biology, Biochemistry, or related field. Alternatively, a Master's degree with 8 years of significant relevant experience may be considered.

* Strong hands-on experience in cell and molecular biology, including mammalian cell culture, mRNA isolation/quantitation by qPCR, sequencing (NGS/Sanger), and protein quantification by ELISA and western blot.

* Experience in oligonucleotide therapeutics is a plus.

* Familiarity with CNS disease models and DNA/RNA editing tools is highly desired.

* Outstanding aptitude for experimental design and execution, efficient assay development and creative problem solving.

* Ability to thrive in a dynamic, fast-paced research environment.

* Collaborative team player with excellent communication skills.



What are the top 3-5 skills, experience or education required for this position?

1. PhD or MS degree in molecular biology, cell biology, neuroscience or biochemistry

2. industry experience in cell and molecular biology

3. Good at mammalian cell culture

4. Familiar with RNA extraction, qPCR, protein quantification with ELISA and Western

5. Experience in oligonucleotide therapeutics is a plus



Type of interview (video, phone or onsite)?

1st Round: 30 min with manager (Virtual)

2nd Round: 2 hours - Manager/team (4)