RWE & Observational Research Lead

Vertex Pharmaceuticals; Boston (MA); Hybrid; USD 132,000 - 198,000; Full time

Job summary

Vertex Pharmaceuticals seeks a Real World Evidence Manager to integrate epidemiology, real world data, and regulatory insight to evaluate outcomes for Vertex’s portfolio. You will partner with Clinical Development, Global Medical Affairs, and other teams to design observational studies, manage vendors, and deliver rigorous analyses that inform decision-making.

The role supports publications and presentations, helps build dashboards, and requires strong communication to translate complex results

Qualifications

• PhD or MS/MPH in epidemiology or related field.
• Minimum 2 years in observational research.
• Formal graduate training in Epidemiology/HEOR.
• Ability to communicate complex results to cross-functional teams.

Responsibilities

• Support focused epidemiologic research for Vertex pipeline and portfolios.
• Ensure scientific rigor for real world data analyses.
• Collaborate with vendors and manage study timelines.
• Support observational study execution teams.
• Develop performance metrics and dashboards for RWE projects.
• Translate findings to non-technical audiences across teams.

Skills

Observational research

Regulatory guidance

Data synthesis

Vendor management

Cross-functional collaboration

Education

PhD / MS / MPH in Epidemiology

Epidemiology/HEOR training

Job description

Vertex Pharmaceuticals seeks a Real World Evidence Manager to integrate epidemiology, real world data, and regulatory insight to evaluate outcomes for Vertex’s portfolio. You will partner with Clinical Development, Global Medical Affairs, and other teams to design observational studies, manage vendors, and deliver rigorous analyses that inform decision-making.

The role supports publications and presentations, helps build dashboards, and requires strong communication to translate complex results