Research Technician III - Immuno-Oncology & Nanoparticles

Baylor College of Medicine; Houston (TX); On-site; USD 42,000 - 64,000; Full time

Job summary

Baylor College of Medicine's Parihar Lab is seeking a Research Technician to support nanoparticle-based cancer immunology research. The role involves in vitro work applying nanoparticles to immune cells and in vivo testing in mouse cancer models, contributing to translational science and biomedicine.

Candidates will isolate immune cells, perform assays such as cytotoxicity and flow cytometry, and collaborate on nanoparticle generation, documentation, and reporting with regular lab meetings and

Qualifications

• Bachelor's degree in a Basic Science or related field; four years may substitute for degree.
• One year of relevant experience.

Responsibilities

• Isolate human peripheral blood immune cells in the lab.
• Expose immune cells to engineered nanoparticles and assess NK cell activity using cytotoxicity assays, ELISA, and flow cytometry.
• Work with Dr. Parihar and collaborators in nanoparticle generation, characterization, and barcoding; complete relevant documents, provide updates, and complete reports.
• Generate and characterize human cell lines derived from blood immune cells.
• Generate tumor-bearing mice for in vivo studies, following tumor growth by in vivo bioluminescence and immune cell editing by flow cytometry.
• Generate CAR-T and CAR-NK cells in vitro and use in in vitro assays and in vivo models.
• Participate in weekly Parihar Lab meetings, Center for Cell and Gene Therapy (CAGT) conferences, and appropriate GMP meetings, as assigned.
• Perform other lab-related job duties as assigned.

Skills

Lab techniques

Data collection

Communication

Education

Bachelor's degree in Basic Science or related field

Master's degree (preferred)

Job description

Baylor College of Medicine's Parihar Lab is seeking a Research Technician to support nanoparticle-based cancer immunology research. The role involves in vitro work applying nanoparticles to immune cells and in vivo testing in mouse cancer models, contributing to translational science and biomedicine.

Candidates will isolate immune cells, perform assays such as cytotoxicity and flow cytometry, and collaborate on nanoparticle generation, documentation, and reporting with regular lab meetings and