Research Technician-CFCE Lab

Dana-Farber Cancer Institute; Boston (MA); On-site; USD 45,000 - 65,000; Full time

Job summary

Dana-Farber Cancer Institute in Boston, MA seeks a Research Technician to assist scientists in performing research, development, and clinical tasks. The role includes setting up and maintaining lab instruments, monitoring experiments, and recording results.

The Center for Functional Cancer Epigenetics focuses on epigenetic alterations and transcriptional regulation in cancer models, including RNA/DNA extraction and advanced sequencing techniques.

Qualifications

• Assist scientists in performing scientific research, development and/or clinical tasks.
• Set up, operation and maintenance of laboratory instruments and equipment.
• Monitor experiments, make observations and record results.
• Maintain a comprehensive lab notebook and manage computer data files.
• Reagents ordering and other paperwork to fill up.

Responsibilities

• Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
• Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors
• Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of

Job description

The Research Technician will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Center for Functional Cancer Epigenetics (CFCE) is dedicated to the
exploration of the key role that epigenetic alterations and abnormal transcriptional regulation play in the development and progression of cancer. A better understanding of these alterations will lead to better diagnosis for cancer and contributions to the knowledge required for the development of new therapeutics exploiting epigenetic mechanisms. The Center's organization and leadership represent a very tight coupling between wet-lab and informatics efforts that provides an unprecedented opportunity to advance the field.

The Research Technician will perform experiments under the supervision of the leading team and will be focused on projects that elucidate epigenetic and transcriptional regulation in wide variety of cancer models. This will involve a variety of genomic techniques including RNA and DNA extraction, nuclei isolation, single cell technology, spatial transcriptomics and ATAC-seq and ChIP-seq. In addition, the candidate will have some lab managerial tasks, such as reagents ordering among other paperwork to fill up.

The candidate will support current team goals and practices by producing high-quality data, being actively involved in troubleshooting experiments, maintaining a comprehensive lab notebook and managing computer data files.

• Set up, adjust, calibrate, clean, maintain and troubleshoot equipment
• Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors
• Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of