Research Senior Associate-Comprehensive Cancer Center

The Ohio State University Wexner Medical Center; Columbus (OH); On-site; USD 60,000 - 80,000; Full time

Job summary

The Ohio State University Wexner Medical Center is seeking a Research Senior Associate to support the center for antibody therapeutics at the Pelotonia Institute for Immuno-Oncology. This role involves conducting advanced in vitro and in vivo research, collaborating with investigators, and managing laboratory operations. Required qualifications include a Master's Degree with relevant experience in biological or health sciences, along with strong analytical and communication skills. The position contributes to significant cancer research advancements.

Qualifications

• Master's Degree required; Doctor’s degree preferred or equivalent experience.
• 1 year of experience required with Master's Degree.
• Strong analytical and communication skills.

Responsibilities

• Perform advanced in vitro and in vivo techniques including molecular biology.
• Collect, analyze, and interpret research data.
• Collaborate with principal investigator to write manuscripts and proposals.
• Monitor and enforce laboratory safety procedures.
• Train research staff and manage daily laboratory operations.

Skills

Advanced in vitro techniques

Advanced in vivo techniques

Molecular biology skills

Strong analytical skills

Communication skills

Education

Master's Degree

Doctor’s degree in biological or health sciences

Tools

Chromatography

SDS-PAGE

ELISA

Flow cytometry

Job description

Position Summary

The Research Senior Associate will assist and support the center for antibody therapeutics (CAT) at the Pelotonia Institute for Immuno-Oncology (PIIO) within the OSUCCC – James. The Associate will participate in planning, executing, and analyzing translational cancer research with focus on antibodies and proteins, antibody drug conjugates, bispecific antibodies, antibody-based CAR‑NK and CAR‑T cell immunotherapy using advanced molecular, cellular and antibody‑based techniques.

Key Responsibilities

• Perform advanced in vitro and in vivo techniques including molecular biology skills such as DNA, RNA extraction, RT‑PCR, etc.; production, purification, and characterization of antibody, antibody drug conjugates, bispecific antibodies, CAR‑T, CAR‑NK and general cell culture skills such as mammalian and bacterial cell growth, etc.; protein biochemistry such as antibody and protein purification, chromatography, SDS‑PAGE, Western blotting, ELISA, flow cytometry, immunostaining, in‑vitro assays and development, ADCC, CDC, IncuCyte or RTCA cytotoxicity assays, biacore or other SPR assays, etc.; and small animal skills such as tail vein, intraperitoneal and subcutaneous injections of cancer cells and tumor xenografts into mice to generate animal models of cancer and of therapeutic agents for experimental therapy, small animal in‑vivo imaging, etc.
• Collect, analyze, and interpret research data; assist with development and implementation of new methodologies.
• Collaborate with principal investigator to write manuscripts, abstracts and research reports for publication in peer‑reviewed journals; assist with the development and preparation of grant proposals to obtain outside funding in support of research; conduct critical analysis of research literature related to research being investigated.
• Monitor and enforce laboratory safety procedures; ensure compliance with institutional and federal regulations.
• Train research staff and manage daily laboratory operations, including procurement and equipment maintenance.
• Perform additional duties as assigned.

Required Qualifications

• Master's Degree required; Doctor’s degree in biological or health sciences strongly preferred, or equivalent experience. 1 year of relevant experience required with Master's Degree, 3 years of relevant experience required with Bachelor's Degree.
• Ability to translate and apply academic knowledge in biological/health science research.
• Experience in antibody/protein, chromatography or antibody‑based research capacity required.
• Strong analytical and communication skills.

Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post‑offer process.

The university is an equal opportunity employer, including veterans and disability.