Research Senior Associate-Comprehensive Cancer Center

Ohio State University; Columbus (OH); On-site; USD 60,000 - 80,000; Full time

Benefits offered by this job

Comprehensive medical, dental, and vision coverage

Paid time off and holidays

Generous retirement plan with employer contributions

Job summary

Ohio State University is looking for a Research Senior Associate in the Comprehensive Cancer Center. This role involves supporting cancer research focused on antibody therapeutics, including tasks like molecular biology, protein characterization, and lab safety compliance. Candidates should have a Master's or Doctoral degree in relevant fields and experience in antibody/protein research. The position offers a collaborative environment and is located in Columbus, Ohio, with full-time hours.

Qualifications

• Master's Degree required, Doctor’s degree preferred.
• 1 year of relevant experience required with Master's Degree.
• Experience in antibody/protein, chromatography or antibody-based research.

Responsibilities

• Perform advanced in vitro and in vivo techniques.
• Collect, analyze, and interpret research data.
• Monitor and enforce laboratory safety procedures.

Skills

Advanced in vitro and in vivo techniques

Molecular biology

Protein characterization

Strong analytical skills

Communication skills

Education

Master's Degree in Biological or Health Sciences

Doctor’s degree in biological or health sciences

Tools

Chromatography

ELISA

SDS-PAGE

Flow cytometry

Job description

Research Senior Associate-Comprehensive Cancer Center page is loaded## Research Senior Associate-Comprehensive Cancer Centerlocations: College of Medicine/Office of Health Sciencestime type: Full timeposted on: Posted Todayjob requisition id: R144039Screen reader users may encounter difficulty with this site. For assistance with applying, please contact [e-mail]. If you have questions while submitting an application, please review these .**Current Employees and Students:**If you are currently employed or enrolled as a student at The Ohio State University, please log in to to use the internal application process.Welcome to The Ohio State University's career site. We invite you to apply to positions of interest. In order to ensure your application is complete, you must complete the following:* Ensure you have all necessary documents available when starting the application process. You can review the additional job description section on postings for documents that may be required.* Prior to submitting your application, please review and update (if necessary) the information in your candidate profile as it will transfer to your application.## Job Title:Research Senior Associate-Comprehensive Cancer Center## Department:CCC | Comprehensive Cancer Center# **Position Summary**The Research Senior Associate will assist and support the center for antibody therapeutics (CAT) at the Pelotonia Institute for Immuno-Oncology (PIIO) under direct supervision of Dr. Zhiwei Hu, Managing Director of the PIIO CAT at the OSUCCC – James. Research Senior Associate will participate in planning, executing, and analyzing translational cancer research with focus on antibodies/proteins, antibody drug conjugates, bispecific antibodies, antibody-based CAR-NK and CAR-T cell immunotherapy using advanced molecular, cellular and antibody-based techniques.# **Key Responsibilities*** Perform advanced in vitro and in vivo techniques including molecular biology skills such as: DNA, RNA extraction, RT-PCR, etc; production, purification and characterization of antibody, antibody drug conjugates, bispecific antibodies, CAR-T, CAR-NK and general cell culture skills such as mammalian and bacterial cell growth, etc; protein biochemistry such as antibody and protein purification, chromatography, SDS-PAGE, Western blotting, ELISA, flow cytometry, immunostaining, in vitro assays and development, ADCC, CDC, IncuCyte or RTCA cytotoxicity assays, biacore or other SPR assays, etc; and small animal skills such as tail vein, intraperitoneal and subcutaneous injections of cancer cells and tumor xenografts into mice to generate animal models of cancer and of therapeutic agents for experimental therapy, small animal in vivo imaging, etc.* Collect, analyze, and interpret research data; assist with development and implementation of new methodologies.* Collaborate with principal investigator to write manuscripts, abstracts and research reports for publication in peer-reviewed journals; assist with the development and preparation of grant proposals to obtain outside funding in support of research; conduct critical analysis of research literature related to research being investigated.* Monitor and enforce laboratory safety procedures; ensure compliance with institutional and federal regulations.* Train research staff and manage daily laboratory operations, including procurement and equipment maintenance.* Perform additional duties as assigned.# **Required Qualifications*** Master's Degree required, Doctor’s degree in biological or health sciences strongly preferred, or equivalent experience. 1 year of relevant experience required with Master's Degree, 3 years of relevant experience required with Bachelor's Degree.* Ability to translate and apply academic knowledge in biological/health science research.* Experience in antibody/protein, chromatography or antibody-based research capacity required.* Strong analytical and communication skills.## Additional Information:The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation’s largest public universities.Pelotonia Institute for Immuno-Oncology (PIIO) is a comprehensive bench-to-bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels - from prevention to treatment and survivorship.The Center for Antibody Therapeutics (CAT) at the PIIO is a specialized technology hub dedicated to the discovery, development, production, optimization, and translation of antibody-based therapeutics from basic science research to preclinical and clinical studies for cancer treatment. The Center will leverage cutting-edge technologies to develop monoclonal antibodies, bispecific antibodies (bsAb), antibody-drug conjugates (ADCs), antibody engineering, and other antibody-based immunotherapies including CAR-T and CAR-NK cells. This center will serve the PIIO research community, clinical teams, and external partners by providing essential expertise and infrastructure to accelerate immuno-oncology research from basic science discovery to translational research, commercialization towards clinical trials in alignment with the overall strategic growth goals of the PIIO.## Location:Biomedical Research Tower (0112)## Position Type:Regular## Scheduled Hours:40## **Shift:**First Shift***Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.***Thank you for your interest in positions at The Ohio State University and Wexner Medical Center. Once you have applied, the most updated information on the status of your application can be found by visiting the section of this site. Please view your submitted applications by logging in and reviewing your status. For answers to additional questions please review the .The university is an equal opportunity employer, including veterans and disability.At Ohio State, you’ll find work that inspires you. We offer roles and growth opportunities in countless fields and specialties — including a job that’s right for ***you***.### Starting day one: Comprehensive benefits.give you options to take care of what matters most to *you* — and opportunities to make adjustments as your life and needs change, including:• Medical, dental and vision coverage, with Ohio State paying a significant portion of the cost.• Paid time off, including sick and vacation time and 11 holidays.• State retirement plan or an alternative retirement plan, both with generous employer contributions.As Buckeyes, we accomplish more together. No matter your role, you’ll be part of creating what people need now: pathways to education, research and health care.Working at Ohio State means you’re part of a team with a strong sense of community and an unwavering commitment to excellence — and, of course, incomparable Buckeye spirit. 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