Research Scientist/Senior Scientist - LC-MS/MS

Eurofins USA Clinical Trial Solutions; Lenexa (KS); In loco; USD 85.000 - 125.000; Tempo pieno

Vantaggi offerti da questo lavoro

Medical, dental and vision coverage

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Descrizione del lavoro

Eurofins USA Clinical Trial Solutions is seeking a Research Scientist/Senior Scientist to advance LC-MS/MS bioanalytical capabilities within a regulated CRO setting. You will develop, validate, transfer, and support analyses for diverse modalities including small molecules, peptides, ADCs, and mAbs.

The ideal candidate brings hands-on LC-MS/MS method development/validation experience and knowledge of FDA/EMA/ICH M10 guidance, contributing to SOPs and process improvements in a collaborative team.

Competenze

• BS, MS, or PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, Chemistry, or a related scientific discipline.
• 3–8+ years of relevant bioanalytical laboratory experience.
• Hands-on experience with LC-MS/MS method development and validation.
• Working knowledge of FDA, EMA, and ICH M10 bioanalytical method validation requirements.
• Experience with small molecules, peptides, oligonucleotides, ADCs, or mAbs.
• Experience supporting regulated bioanalytical studies and routine sample analysis.
• Strong technical writing and documentation skills.
• Experience in a CRO, pharmaceutical, or biotechnology environment.
• Familiarity with hybrid LC‑MS/LBA approaches.
• Experience with laboratory informatics systems, including LIMS and chromatography data systems.
• Knowledge of assay validation, sample management, and regulated study workflows.

Mansioni

• Develop, optimize, qualify, and validate LC-MS/MS bioanalytical methods for regulated studies.
• Perform sample preparation, instrument operation, data analysis, and troubleshooting.
• Support routine sample analysis for preclinical and clinical studies.
• Assist with assay validation activities in accordance with FDA, EMA, and ICH M10 guidance.
• Analyze and interpret data and contribute to study reports and technical documentation.
• Author and revise SOPs, work instructions, validation protocols, and technical reports.
• Support onboarding, qualification, and maintenance of LC-MS/MS instrumentation and associated laboratory systems.
• Collaborate with cross-functional teams including Quality Assurance, Operations, Project Management, and Scientific Leadership.
• Identify and implement opportunities for process improvements and operational efficiencies.
• Maintain compliance with applicable GLP, GCP, and company quality requirements.

Conoscenze

LC-MS/MS method development

Bioanalytical method validation

Regulated bioanalysis

Data analysis

Technical writing

SOP development

LIMS

LC-MS/MS platforms

Formazione

Analytical Chemistry / Biochemistry / Pharmaceutical Sciences (BS/MS/PhD)

Strumenti

Waters LC-MS/MS

Sciex LC-MS/MS

Thermo Fisher LC-MS/MS

Shimadzu LC-MS/MS

Descrizione del lavoro

Research Scientist/Senior Scientist - LC-MS/MS

• Full-time

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in‑vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.

We are seeking a Research Scientist / Senior Scientist to support the growth of our bioanalytical LC-MS/MS capabilities within a regulated CRO environment. This role will contribute to method development, validation, transfer, and support sample analysis for a diverse range of therapeutic modalities, including small molecules, peptides, oligonucleotides, antibody‑drug conjugates (ADCs), and monoclonal antibodies.

The successful candidate will bring hands‑on experience in regulated bioanalysis and will work closely with scientific, operational, and quality teams to implement and execute assays in accordance with FDA, EMA, and ICH M10 guidance. In addition to laboratory-based activities, this individual will support SOP development, equipment onboarding, process improvement initiatives, and the integration of LC-MS/MS services into an established bioanalytical testing organization.

This is an excellent opportunity for a scientifically mature and collaborative professional who enjoys both technical problem‑solving and helping build new capabilities in a growing laboratory environment.

Here's what you'll do:

• Develop, optimize, qualify, and validate LC-MS/MS bioanalytical methods for regulated studies.
• Perform sample preparation, instrument operation, data analysis, and troubleshooting.
• Support routine sample analysis for preclinical and clinical studies.
• Assist with assay validation activities in accordance with FDA, EMA, and ICH M10 guidance.
• Analyze and interpret data and contribute to study reports and technical documentation.
• Author and revise SOPs, work instructions, validation protocols, and technical reports.
• Support onboarding, qualification, and maintenance of LC-MS/MS instrumentation and associated laboratory systems.
• Collaborate with cross-functional teams including Quality Assurance, Operations, Project Management, and Scientific Leadership.
• Identify and implement opportunities for process improvements and operational efficiencies.
• Maintain compliance with applicable GLP, GCP, and company quality requirements.

The ideal candidate:

• BS, MS, or PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, Chemistry, or a related scientific discipline.
• 3–8+ years of relevant bioanalytical laboratory experience.
• Hands‑on experience with LC-MS/MS method development and validation.
• Working knowledge of FDA, EMA, and ICH M10 bioanalytical method validation requirements.
• Experience with one or more of the following analyte classes:
  • Small molecules
  • Peptides
  • Oligonucleotides
  • Antibody‑drug conjugates (ADCs)
  • Monoclonal antibodies (mAbs)
• Experience supporting regulated bioanalytical studies and routine sample analysis.
• Strong technical writing and documentation skills.
• Excellent troubleshooting, organizational, and communication skills.
• Experience in a CRO, pharmaceutical, or biotechnology environment.
• Familiarity with hybrid LC‑MS/LBA approaches.
• Experience with Waters, Sciex, Thermo Fisher, or Shimadzu LC‑MS/MS platforms.
• Experience supporting SOP development and laboratory process implementation.
• Experience with laboratory informatics systems, including LIMS and chromatography data systems.
• Knowledge of assay validation, sample management, and regulated study workflows.

The position is full-time, Monday-Friday, 8 a.m.- 5 p.m., with overtime as needed.

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Clinical Trial Solutions is a Disabled and Veteran Equal Employment Opportunity employer.