Research Scientist J.Lee Lab

Massachusetts General Hospital; Boston (MA); Hybrid; USD 60,000 - 96,000; Full time

Job summary

Massachusetts General Hospital invites applications for a Summer Research position at The General Hospital Corporation, driving genetic association analyses and validating target genes for therapeutic discovery.

You will design and perform cell-based, biochemical, and in vivo experiments, maintain cell lines, and collaborate with informatics teams to integrate data and present results in cross-functional projects.

Qualifications

• PhD or doctoral level training in relevant field required.
• Strong research and problem-solving abilities.
• Ability to contribute to scientific publications.

Responsibilities

• Design and perform genetic association analysis.
• Design, plan, and execute cell-based, biochemical, and in vivo experiments to validate target genes.
• Maintain cell lines and isolate primary cells for assays.
• Collaborate with informatics and computational scientists to integrate datasets.
• Characterize mechanism of action studies for compounds.
• Work with team to design research plans and meet timelines.
• Troubleshoot and solve scientific problems independently.
• Train investigators in techniques related to small animal surgery and molecular biology.

Skills

Excellent research skills

Scientific competence

Broad knowledge in field

Creativity and originality

Independent judgment and leadership

Publications contribution

Education

Doctorate or PhD in related field

Job description

Site: The General Hospital Corporation

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

Summer: Drives research projects scientically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientic success of the project.

• oDesign and perform genetic association analysis.
• oDesign, plan, and execute cell-based, biochemical, and in vivo experiments necessary to validate target genes for therapeutic discovery.
• oMaintain cell lines and isolate primary cells for use in cell-based assays.
• oWork with informatics and computational scientists to integrate and interpret screening and functional genomic data sets.
• oPerform detailed characterization and cellular mechanism of action studies of chemically optimized compounds.
• oPerform mouse genetic linkage analysis to define genes affecting genome instability
• oWork with team to design and execute research plans to ensure that critical project requirements, timelines, and deliverables are met.
• oTroubleshoot and solve scientific problems independently.
• oIdentify, investigate and implement new technologies based on scientific needs.
• oEffectively present results in cross-functional project teams.
• oDesign, execute, and interpret research experiments.
• oTrain investigators in techniques relating to small animal surgery, molecular biology, and vector construction.
• oInvestigates, creates and develops new methods and technologies for research advancements
• oAssist in laboratory management.
• oContribute to scientific literature and present research at scientific forums

Qualifications

Education
Doctorate Related Field of Study required

Can this role accept experience in lieu of a degree?
No

Licenses and Credentials

Experience
Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required

Knowledge, Skills and Abilities

• - Excellent research skills.
• - Demonstrated evidence of specific scientific competence in field.
• - Demonstrated broad knowledge of field.
• - Evidence of potential for scientific creativity and original though.
• - Able to exercise independent judgment and leadership.
• - Ability to contribute to publications.

The salary range for this position is $60,000 to $96,000 annually.

Additional Job Details (if applicable)

Remote Type: Hybrid

Work Location: 185 Cambridge Street

Scheduled Weekly Hours: 40

Employee Type: Regular

Work Shift: Day (United States of America)

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.