Research Scientist, High-Throughput Chemistry & Automation

Iambic; San Diego (CA); On-site; USD 113,000 - 156,000; Full time

Benefits offered by this job

Industry-leading pay

Company-paid healthcare

Flexible spending accounts

Voluntary life insurance

401K matching

Uncapped vacation

Job summary

Iambic Therapeutics in San Diego, CA is seeking a skilled Research Scientist to join the Discovery Chemistry team. You will design, optimize, and execute high-throughput experiments to accelerate compound library campaigns, leveraging automation and HTE platforms.

The role requires a strong background in organic synthesis, catalysis, and reaction development, with collaboration across chemistry, biology, AI/ML, and software groups to deliver impactful results.

Qualifications

• Ph.D. in Organic Chemistry or MS with substantial industry experience.
• Large experience with High Throughput Chemistry and parallel synthesis.
• Experience with automation, robotics, and automated analytical/purification systems.

Responsibilities

• Design and execute parallel synthetic methods to create large compound libraries.
• Develop novel synthetic methodologies with automation compatibility and HTE scalability.
• Translate routes from bench-scale to high-throughput automated processes.
• Oversee operation and advancement of the chemistry toolkit and automated synthesis equipment.
• Analyze results and communicate findings to cross-functional teams.
• Ensure lab work follows safety protocols and ELN data practices.
• Collaborate across chemistry, biology, software, and automation teams.
• Identify bottlenecks and troubleshoot automated processes to ensure continuity.

Skills

High Throughput Chemistry

Parallel Synthesis

Automation familiarity

Communication skills

Education

PhD in Organic Chemistry

MS in Organic Chemistry

Tools

Laboratory automation

Liquid handling robotics

Automated analytical systems

Automated purification systems

Job description

Iambic Therapeutics in San Diego, CA is seeking a skilled Research Scientist to join the Discovery Chemistry team. You will design, optimize, and execute high-throughput experiments to accelerate compound library campaigns, leveraging automation and HTE platforms.

The role requires a strong background in organic synthesis, catalysis, and reaction development, with collaboration across chemistry, biology, AI/ML, and software groups to deliver impactful results.