Research Scientist, Biologics Analytics

Vertex Pharmaceuticals LLC; Boston (MA); On-site; USD 104,000 - 156,000; Full time

Job summary

Vertex Pharmaceuticals LLC in Boston, MA, is seeking a Research Scientist to join the Biologics Analytics group. This lab‑based role focuses on developing LC–MS methods to characterize proteins, antibodies, and lipid nanoparticles, delivering detailed product insights to support program advancement.

The ideal candidate has a PhD or equivalent in biochemistry with relevant experience and a proven ability to work independently and with cross‑functional teams in a fast-paced research setting.

Qualifications

• Ph.D. in biochemistry or related field with 0–3 years post‑doc, or Masters with 8+ years of experience.
• Experience in LC-MS based analytical method development.
• Strong collaboration, independence and attention to detail.

Responsibilities

• Work collaboratively across therapeutic areas to provide detailed product characterization.
• Develop, execute and optimize LC and MS based methods for proteins, antibodies, scaffolds, bioconjugates and lipid nanoparticles.
• Serve as SME for LC-MS analysis of proteins and lipid nanoparticles.
• Collaborate on developability/manufacturability assessment to support product advancement.
• Transfer of analytical methods and provide technical support.
• Participate actively in group and cross-disciplinary project team meetings.

Skills

LC-MS analysis

Protein characterization

Cross-functional collaboration

Laboratory automation

Education

PhD in Biochemistry

Masters in Biochemistry

Tools

LC-MS systems

Job description

## Research Scientist, Biologics AnalyticsApply: Boston, MA: Full time: Posted Today: End Date: October 2, 2026 (3 days left to apply): REQ-30291**Job Description****Job Description**Vertex is seeking a talented Research Scientist to join a collaborative research team focused on Biologics discovery and optimization in Boston, MA. The group’s mission is to deliver next generation biologics and genetic therapies impacting several therapeutic areas. We are looking for a candidate with a strong desire to deliver innovative new medicines to patients in need. In this *lab-based role*, the ideal candidate is strongly experienced in LC-MS based analytical method development and characterization of biologics including antibodies and antibody-like scaffolds, bioconjugates, and lipid nanoparticles. The candidate should be independent, accustomed to taking initiative, and bring enthusiasm and intellectual curiosity to Vertex’s fast-paced research environment. **Key Responsibilities:** * Work collaboratively amongst several therapeutic areas and modalities to provide detailed product characterization to support program advancement* Develop, execute and optimize LC and MS-based methods for the characterization of proteins, antibodies, antibody-like scaffolds, bioconjugates, and lipid nanoparticles* Serve as the subject matter expert for LC-MS based analysis of protein and lipid nanoparticles* Collaborate towards developability/manufacturability assessment in support of product advancement* Transfer of analytical methods and technical support* Active participation in group and cross-disciplinary project team meetings **Knowledge and Skills:** * Proficient in protein and lipid nanoparticle characterization by liquid chromatography and mass spectrometry* Familiarity with instrument integration and scheduling tools* Strong understanding of biologics and lipid nanoparticle manufacturing and critical quality attributes* Track record of productivity* Ability to work effectively with cross-functional teams and prioritize multiple programs* Strong ownership, scientific curiosity, attention to detail, and commitment to technical excellence **Education and Experience:*** Ph.D. (or equivalent degree) in biochemistry or related disciplines and 0-3 years of relevant post-doctoral employment experience, or* Masters Degree (or equivalent degree) in biochemistry or related disciplines and 8+ years of relevant employment experience At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.**Pay Range:**$104,200 - $156,200**Disclosure Statement:**The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Flex Designation:**On-Site Designated**Flex Eligibility Status:**In this **On-Site** designated role, you will work **five days per week on-site** with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.