Research Scientist - Bioinformatics Analyst

University of Colorado; United States; Hybrid; USD 90,000 - 130,000; Full time

Benefits offered by this job

ECO Pass

Tuition Benefit

Holiday/Vacation/Sick leave

Job summary

University of Colorado Anschutz is seeking a Bioinformatics Programmer to manage and analyze data from NEXT- generation sequencers, collaborating with faculty on genomic projects. You will develop tools, publish methods, and co-author studies while expanding your skillset in a dynamic team.

The role emphasizes data quality control, integration of diverse genomics data, and the creation of pipelines for routine analyses within a hybrid on-campus setting.

Qualifications

• Master's degree in Computational Biology, Systems Biology, Computer Science or related field.
• Minimum 3 years programming experience with Python, R, Java, Go, Bash, SQL, MySQL.
• Minimum 3 years tools/library experience with Git, Linux, Scikit-Learn, Numpy, Pandas, Samtools, Bedtools, Bowtie2, STAR, Nextflow, Snakemake.

Responsibilities

• Work with multi-omics data analysis and integration approaches.
• Perform robust data quality control and validation.
• Analyze sequencing data types including single-cell, RNA-seq, ChIP-seq, ATAC-seq, Hi-C, bisulfite, and WGS.
• Collaborate with bench scientists to understand research goals.
• Integrate genomics data and present computational results concisely.
• Design and implement standard and customized genomics pipelines.
• Conduct meta-analyses of GEO and other datasets as assigned.

Skills

Python

R

SQL

Bash

Java

Go

Education

Masters in Computational Biology

Tools

Git

Linux

Scikit-Learn

Numpy

Pandas

Samtools

Bedtools

Bowtie2

STAR

Nextflow

Snakemake

Job description

University of Colorado Anschutz, Department: Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplant

Job Title: Research Scientist - Bioinformatics Analyst

Position #: 00798581 - Requisition #:41252

Job Summary

We have an exciting opportunity to join our team as a Bioinformatics Programmer. The Center for Cancer and Blood Disorders (CCBD) at the University of Colorado/Anschutz Medical Campus is seeking a highly motivated, enthusiastic individual to manage and analyze data generated by Next-Generation DNA sequencers in conjunction with the experiments performed by our faculty. This is a great opportunity to quickly acquire new skills, develop and publish new tools and methods, analyze challenging datasets and be a co-author on multiple published studies.

Key Responsibilities

• Work with emerging approaches for analyzing multi-omics data analysis and integration (15%)
• Perform robust data quality control and validation (15%)
• Analyze various types of sequencing data analysis (e.g. single cell sequencing, RNA-seq, ChIP-seq, ATAC-seq, Hi-C-seq, bisulfite sequencing, whole-genome sequencing) (15%)
• Work closely with bench scientists to understand and help accomplish their research goals (12%)
• Integrate different types of genomics data and prepare concise presentations of computational results (12%)
• Design, implement, execute standard pipelines for routine genomics data analyses, and customized pipelines for collaborative research projects (11%)
• Perform robust data quality control and validation (10%)
• Perform other duties (such as meta-analyses of existing GEO deposited and other data sets) as assigned by faculty collaborators (10%)

Work Location

Hybrid - this role is eligible for a hybrid schedule of 3 days per week on campus and as needed for in-person meetings.

Why Join Us

The Hematology/Oncology/Bone Marrow Transplant Section within the Pediatrics Department is nationally recognized for providing excellent consultation, clinical care, and surgery for children and adolescents with cancer and blood disorders. Faculty in the Section study childhood bleeding disorders, brain and blood tumors, bone marrow failure and sickle cell disease. Our renowned team of multidisciplinary experts provides thousands of children who are fighting cancer and blood disorders with world-class care and cutting-edge treatments - all while pioneering new therapies and cures through groundbreaking research.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year (based on percentage of time)
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 11/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service
• There are many additional perks & programs with the CU Advantage .

Qualifications

Minimum Qualifications

Applicants must meet minimum qualifications at the time of hire.

• Graduation from an accredited university with a Masters in Computational Biology, System Biology, Computer Science or related field
• Minimum of 3 years of programming language experience with Python, R, Java, Go, Bash, SQL, MySQL
• Minimum of 3 years of tools and library experience with Git, Linux, Scikit-Learn, Numpy, Pandas, Samtools, Bedtools, Bowtie2, STAR, Nextflow, Snakemake

Condition of Employment

• Must be willing and able to pass a national criminal background check

Preferred Qualifications

• Graduation from an accredited university with a PhD in Computational Biology, System Biology, Computer Science or related field
• Prior experience with brain cancer disease models
• Experience with stem cell biology and relevant assays (flow cytometric analysis and flow sorting of stem or progenitor population
• Prior experience in chromatin biology

Knowledge, Skills and Abilities

• Ability to function autonomously but exercise sound judgment in seeking appropriate supervision
• Skilled in communicating effectively and facilitating group processes
• Ability to establish and maintain effective working relationships with researchers, and other team members
• Comply with all standard operating procedures and quality control systems per the University of Colorado policy
• Knowledge of Computational Biology programming languages, tools and libraries
• Demonstrates the proficiency in computer software, equipment operation, and research technical skills