Research Lab Tech I NEUROLOGY rl

2200 The Brigham and Women's Hospital, Inc.; Boston (MA); On-site; USD 29,000 - 40,000; Full time

Job summary

The Brigham and Women's Hospital, part of Mass General Brigham, seeks a Research Lab Tech I to investigate microbiome and immune roles in neurologic disease using animal models. You will execute diverse experiments, document findings, and maintain lab notes at a professional level.

Ideal candidates have some lab experience and are pursuing a bachelor's degree with on-the-job training provided for specific procedures.

Qualifications

• Bachelor's degree in related field required.
• 1–2 years of laboratory experience preferred.
• Ability to work independently and as part of a team.
• Ability to multi-task with attention to detail.
• Good manual dexterity and lift up to 30 lbs.

Responsibilities

• Administers bacteria or immunomodulatory agents to animal models.
• Handles mice, including treatment administration and behavioral tests.
• Learns to operate Flow Cytometry machinery.
• Performs ELISA, DNA/RNA purification and cloning.
• Maintains mouse colonies and records of strains/breeding.
• Cultures bacteria from the microbiome and maintains stocks.

Skills

Lab techniques

Mice handling

Flow cytometry

PCR ELISA

Data analysis

Education

Bachelor's Degree in Related Field

Tools

Flow Cytometer

ELISA Kits

PCR Machines

DNA Purification Kits

Job description

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The Ann Romney Center for Neurologic Diseases is seeking to hire a highly qualified and motivated Research Lab Tech I to investigate the role of the microbiome and the immune system in models of neurologic disease. Working under general supervision of Rafael Rezende, the Tech will execute protocols involving a variety of routine and non-routine experiments at a professional level, including but not exclusively involving administering treatments to animal models of neurologic disease, characterizing behavior and pathology in animal models, performing flow cytometry, ELISAs, DNA extraction, PCR, and culturing bacteria. The Research Lab Tech will record test results in an orderly fashion and maintain accurate laboratory notes as well as maintain laboratory supplies. An ideal candidate will have some experience with laboratory procedures and working with mice. In addition, training will be provided on the job for specific procedures. Seeking candidates that can commit to the position for two years. Candidates who are in the process of completing their bachelor’s degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.

Essential Functions

• As directed, administers bacteria or immunomodulatory agents to animal models of neurologic diseases.
• Will be required to handle mice including treatment administration (intraperitoneal, subcutaneous, and intravenous injections) and behavioral tests.
• Will be required to learn to operate Flow Cytometry machinery.
• Will be required to perform routine immunology techniques such as ELISA, western blot and basic procedures on laboratory animals; and molecular biology techniques like RNA purification, DNA purification and cloning.
• Will be required to maintain mouse colonies and to keep record of mouse strains and breeding.
• Will be required to perform cell culture, including culture and maintenance of various cell lines and hybridomas.
• Will be required to cultures bacteria from the microbiome and maintains stocks.
• Performs routine molecular experiments, including DNA extraction, and 16S rRNA amplicon library preparation.
• Maintains and orders supplies when needed.
• Assists with cleaning and maintaining the laboratory area in a neat and orderly condition.
• Maintains laboratory notebook of daily activities including all experiments and procedures.
• Conducts literature searches and review, compiling information from journals and suggesting uses of new techniques of research and laboratory techniques, consulting with other researchers and techniques to exchange information.
• Attends courses in safety procedures for the handling, storage and disposal of biohazardous, infectious, radioactive and toxic substances, ensuring that all laboratory activities are carried out in compliance with such procedures.
• Perform laboratory experiments following established protocols and procedures.
• Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
• Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
• Record experimental data accurately and maintain organized records of procedures, protocols, and results.
• Compile and analyze data using appropriate statistical and analytical methods.
• Assist in data interpretation and presentation, contributing to research findings and reports.
• Performs other duties as assigned or as position requires.

Qualifications

• Education Bachelor's Degree Related Field of Study required
• Can this role accept experience in lieu of a degree? Yes
• Experience Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred
• Knowledge, Skills and Abilities
  • Must have a sound understanding of laboratory practices and procedures, usually acquired through one to three months on the job training.
  • Ability to manage work processes in a neat and orderly way, to follow instructions, and to work both independently and collaboratively as a member of a team.
  • Ability to multi-task and prioritize work with attention to detail and punctuality.
  • On own initiative, ability to identify potential problems and troubleshoot problems as necessary.
  • Must have good manual dexterity and be able to carry items weighing up to 30 lbs.
  • Good organizational and record keeping skills, detail oriented.
  • Good interpersonal and oral and written communication skills.
  • Ability to demonstrate professionalism.
  • Sound degree of computer literacy.
  • Strong theoretical and practical knowledge of laboratory techniques and procedures.
  • Familiarity with common laboratory equipment and instruments used in research experiments.
  • Proficiency in data collection, analysis, and scientific software tools.
  • Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
  • Strong problem-solving skills and the ability to troubleshoot technical issues.
  • Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Additional Job Details

• Remote Type Onsite
• Work Location 60 Fenwood Road
• Scheduled Weekly Hours 40
• Employee Type Regular
• Work Shift Day (United States of America)
• Pay Range $21.00 - $29.01/Hourly Grade 5
• Additional Job Details (if applicable) Remote Type Onsite Work Location 60 Fenwood Road Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $21.00 - $29.01/Hourly Grade 5

Benefits Summary

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth.

EEO Statement: 2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

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At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline. Combat disease. Hold a hand. Help people. Impact the world. Mass General Brigham is a passionate, welcoming community where minds meet caring hearts. Come be a part of the world’s most powerful force in medicine, where every role is important in changing lives. Are you ready? Our history includes New England hospitals founded over 200 years ago, some of the first and most prestigious hospitals in the world. Built on the legacy of two leading academic medical centers, we’re more than a system—we’re leaders in the practice of medicine. Mass General Brigham is committed to serving the community. We are dedicated to enhancing patient care, teaching and research, and taking a leadership role as an integrated health care system. We recognize that increasing value and continuously improving quality are essential to maintaining excellence.