Research Fellow - Chekuri Lab

Massachusetts Eye and Ear; Boston (MA); Sur place; USD 72 000 - 74 000; Plein temps

Résumé du poste

Massachusetts Eye and Ear seeks a postdoctoral fellow to join an NIH-funded program focused on understanding inherited retinal degenerative diseases and developing genetic therapies. The fellow will lead mentored projects using mouse models, retinal cells, and genomics to evaluate therapeutic approaches, with collaboration across institutes.

The role involves in vitro and in vivo experiments, data analysis, manuscript preparation, and regular progress reviews with the mentor.

Qualifications

• Doctoral degree required (MD/PhD).
• Experience in retinal degeneration research is desirable.
• Strong conceptual and technical skills in molecular biology and genomics.

Responsabilités

• Review and summarize literature on retinal degeneration, ocular genomics, and gene therapy.
• Design, perform, and troubleshoot in vitro and in vivo experiments.
• Work with mouse models, retinal/RPE tissues, cell-based systems, and molecular assays.
• Analyze molecular, histological, imaging, functional, and genomic data.
• Maintain organized experimental records and project milestones.
• Present findings in lab meetings, seminars, and conferences; contribute to manuscripts.

Formation

Doctoral degree (MD or PhD)

Outils

Mouse models

AAV-based gene therapy

Ocular genomics

Description du poste

Site: Massachusetts Eye and Ear InfirmaryMass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.Job SummaryProposes and undertakes a mentored, innovative project or challenge to develop novel techniques for Ophthalmic Treatments. Designs and performs experiments, analyzes and presents the outcome.QualificationsEducation MD/PhD or equivalentCan this role accept experience in lieu of a degree? NoPay Range: $71,750.00 - $73,544.00/AnnualAdditional Job Details (if applicable)POSITION SUMMARY:The Chekuri Lab is seeking a postdoctoral fellow to join an NIH-funded research program focused on understanding the molecular mechanisms of inherited retinal degenerative diseases and developing genetic therapies for these conditions. The project uses mouse models, retinal cell and molecular biology approaches, ocular genomics, and AAV-based strategies to study disease mechanisms and evaluate therapeutic approaches.The postdoctoral fellow will lead a mentored research project involving in vitro and in vivo experiments, molecular and functional outcome analyses, data presentation, manuscript preparation, and collaborative project development. This position is a good fit for a candidate interested in retinal degeneration, ocular genomics, gene therapy, and translational vision research.The lab is based at the Schepens Eye Research Institute in the Grousbeck Gene Therapy Center and has close associations with the Ocular Genomics Institute and the Department of Ophthalmology at Harvard Medical School. The fellow will be part of a highly collaborative vision research community with access to resources in retinal disease genetics, ocular gene therapy, genomics, imaging, animal models, and translational research.ESSENTIAL FUNCTIONS:Review and summarize relevant literature in retinal degeneration, ocular genomics, and gene therapy.Design, perform, and troubleshoot in vitro and in vivo experiments.Work with mouse models, retinal/RPE tissues, cell-based systems, and molecular biology assays.Analyze molecular, histological, imaging, functional, and genomic data.Maintain organized experimental records, protocols, and data files.Meet regularly with the mentor to review progress and project milestones.Present findings in lab meetings, seminars, conferences, and project discussions.Contribute to manuscripts, abstracts, posters, reports, and grant-related materials.Attend ARVO meetings, seminars, and training opportunities.EDUCATION AND EXPERIENCE:Doctoral degree (MD or PhD)WORKING CONDITIONS:Lab setting.PHYSICAL REQUIREMENTS:Possible lifting of 10 to 20 lbs., depending on nature of chosen project(s).HIPAA Privacy Training and SanctionsAll employees who have access to health information whose confidentiality is protected by the HIPAA Privacy Rule are required by the Rule to receive training so that they have an understanding and knowledge of the Privacy Rule that corresponds to their job responsibilities and of the group health plan’s policies and procedures that impact on their job duties. Training on the requirements of the HIPAA Privacy Rule and the plan’s health information policies and procedures under the direction of the institution’s privacy officer is a pre-requisite for this position.Employees who violate the requirements of the HIPAA Privacy Rule will be subject to discipline, up to and including termination.This description is intended to indicate essential tasks and levels of work difficulty that will be required of positions that will be given this title. It is not intended to limit or in any way modify the right of supervisors to assign, direct, or control the work of staff members under their supervision. The use of a particular expression or illustration describing duties shall not be held to exclude other duties not mentioned but that are of similar kind or level of difficulty.Remote TypeOnsiteWork Location20 Staniford StreetScheduled Weekly Hours40Employee TypeRegularWork ShiftDay (United States of America)EEO Statement:5110 Massachusetts Eye and Ear Infirmary is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.Mass General Brigham Competency FrameworkAt Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.