Postdoctoral Research Fellow Neurology CTN Lab

Brigham and Women's Hospital, Inc.; Boston (MA); On-site; USD 70,000 - 72,000; Full time

Job summary

The Chitnis Translational Neuroimmunology Laboratory at Brigham and Women's Hospital, Inc. invites applications for a Postdoctoral Research Fellow in Multiple Sclerosis and Neuroimmunological Disorders.

The role focuses on Epstein-Barr virus involvement in MS and novel therapeutic targets, using human samples and disease models, with team-based collaboration across bioinformatics and clinical teams.

Qualifications

• MD/PhD or equivalent doctoral degree required.
• Experience with human samples and/or animal models.
• Strong communication and inter-personal skills.

Responsibilities

• Perform single cell transcriptomic and multiome analyses.
• Conduct proteomic analyses.
• Run and analyze flow cytometry experiments (FACS).
• Culture cells and perform related analyses.
• Perform RT-PCR and protein assays (Western/ELISA).
• Collaborate with biostatistics team for data analysis.

Skills

Single cell transcriptomics

Proteomics

Flow cytometry

RT-qPCR

Molecular biology techniques

Biostatistics

Scientific writing & presentations

Education

MD/PhD or equivalent

Tools

R

Python

Bioinformatics software

Job description

Site: The Brigham and Women's Hospital, Inc.Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.Job SummaryPostdoctoral Research Fellow Position in Multiple Sclerosis and Neuroimmunological DisordersThe Chitnis Translational Neuroimmunology Laboratory is seeking a highly motivated post-doctoral fellow to join the team of researchers working on multiple sclerosis and neuroimmunological disorders, with a focus on understanding the role of Epstein Barr virus in multiple sclerosis, as well as novel therapeutic targets. Studies include human control and disease samples, with correlation to clinical outcomes. The ideal candidate will have a background in immunology basic research and/or molecular biology and computation with experience in techniques including proteomic and single cell transcriptomic analysis, flow cytometry, cell culture and RT-qPCR. The postdoctoral fellow will function as part of a team of researchers which includes bench scientists, clinicians, bioinformatics, data analysts and trainees.Prioritized candidates should demonstrate excellent scientific productivity, evidenced by high-quality publications, and be highly-motivated to conduct independent research. Candidates should have a strong background in molecular biology techniques and the ability to conduct research using human samples and/or animal models. He/she should also be competent in FACS and single-cell techniques. Additionally, candidates should display good communication, presentation and inter-personal skills. M.D., Ph.D., or equivalent is required. A minimum two-year commitment is required.Principal duties of responsibility include:- Single cell transcriptomic and multiome analysis- Proteomic analysis- Conduct of flow cytometry and analysis for specific projects, subject groups- Conduct of cell culture and analysis for specific projects, subject groups- RT-PCR, Western blot, ELISA skills- Conduct of biostatistical analysis in conjunction with biostats team- Understanding of disease state and data variables- Drafting manuscripts- Scientific presentations to lab team and at conferences- Participation in team laboratory projects as neededQualificationsApplicants are expected to have M.D., Ph.D. or equivalent doctoral degreePrioritized candidates should demonstrate excellent scientific productivity, evidenced by high-quality publications, and be highly-motivated to conduct independent research. Candidates should have a strong background in immunology and molecular biology techniques and the ability to conduct research using animal models of disease as well as human samples. Additionally, candidates should display good communication and inter-personal skills. M.D., Ph.D., or equivalent is required. A minimum two-year commitment is required. The salary for this position ranges from $70,000 to $71,750.Additional Job Details (if applicable)We’re excited to learn more about you! To apply for this position, please email your CV and cover letter directly to Dr Tanuja Chitnis at [e-mail] and Dr Emilie Kruzel at [e-mail]. Please do not apply through this link.Remote TypeOnsiteWork Location60 Fenwood RoadEEO Statement:2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.Mass General Brigham Competency FrameworkAt Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.