Research Associate Support Resource - Molecular Biology & Cell-basedAssay(Analytical Development)

SGS Consulting; California City (CA); In loco; USD 90.000 - 120.000; Tempo pieno

Descrizione del lavoro

SGS Consulting is seeking a highly motivated scientist to develop, optimize, and execute analytical assays for proteins, DNA, and AAV nanoparticles. The role covers QC transfer, data interpretation, and rigorous documentation in a fast-paced team.

You will work on mammalian cell-based and PCR-based assays, including ELISA, ddPCR/qPCR, and related analytics, while maintaining compliant records and contributing to cross-functional projects.

Competenze

• B.S. in Biology, Biochemistry, Molecular Biology, or a related discipline.
• Experience in analytical method development and assay transfer.
• Experience in basic statistical analysis.
• 1+ years of industry experience in pharmaceutical or biotechnology environments.

Mansioni

• Develop, optimize, and execute analytical assays for proteins, DNA, AAV nanoparticles, and related cell-based assays.
• Perform routine testing using established SOPs and regulatory guidelines, incl. ddPCR/qPCR, ELISA, and mammalian cell-based assays.
• Support assay transfer to internal partners including documentation, troubleshooting, and method comparability.
• Analyze experimental data, assess data quality, determine applicability to project goals, draw conclusions, and make data-driven recommendations.
• Author, review, and revise experimental procedures, protocols, and technical reports.
• Maintain accurate, timely, and compliant records of analytical development activities in lab notebooks, ELN, and data systems.
• Summarize and present experimental results in meetings and participate in report writing.
• Contribute to a collaborative laboratory environment by sharing technical insights, supporting cross-functional projects, and improving workflows.

Conoscenze

Mammalian cell-based assays

PCR-based assays (qPCR, ddPCR)

ELISA

Mammalian cell culture

DNA/RNA/protein isolation

RT-qPCR

Data analysis

Formazione

Bachelor's degree in Biology/Biochemistry/Molecular Biology or related

Strumenti

Microsoft Office

ELN

Descrizione del lavoro

Job Responsibilities:

• Develop, optimize, and execute analytical assays for proteins, DNA, adeno-associated viral (AAV) nanoparticles, and related cell-based assays.
• Perform routine testing using established SOPs and applicable regulatory guidelines, including ddPCR/qPCR, ELISA, and mammalian cell-based assays.
• Support assay transfer to internal partners (QC, testing, and research teams), including documentation, troubleshooting, and method comparability.
• Analyze experimental data, assess data quality, determine applicability to project goals, draw conclusions, and make data-driven recommendations.
• Author, review, and revise experimental procedures, protocols, and technical reports.
• Maintain accurate, timely, and compliant records of analytical development activities in laboratory notebooks, ELN, and data systems.
• Summarize and present experimental results in meetings and participate in report writing.
• Contribute to a collaborative laboratory environment by sharing technical insights, supporting cross-functional projects, and improving workflows.

Skills:

• Proficiency in mammalian cell-based assays and PCR-based assays (qPCR, ddPCR).
• Hands-on experience performing quantitative assays such as ELISA for characterization of proteins, nucleic acids, viruses, or other biological products.
• Strong experience with sterile technique and mammalian cell culture, including cell maintenance, expansion, characterization, and banking.
• Working knowledge of molecular biology techniques including DNA/RNA/protein isolation, cDNA synthesis, RT-PCR, qPCR, and digital PCR.
• Ability to independently plan, execute, troubleshoot, and document experiments in a fast-paced, collaborative environment.
• Strong analytical thinking, attention to detail, and commitment to generating high-quality, reproducible data.
• Excellent written and verbal communication skills for presenting technical data to technical and non-technical audiences.
• Proficiency with Microsoft Office and standard data analysis and documentation tools.

Education/Experience:

• Experience working with Adeno-Associated Virus (AAV).
• Experience in analytical method development and assay transfer.
• Experience in basic statistical analysis.
• B.S. in Biology, Biochemistry, Molecular Biology, or a related discipline.
• 1+ years of industry experience in pharmaceutical or biotechnology environments.