Research Associate - In Vitro Biology & siRNA

Energy Jobline ZR; San Diego (CA); On-site; USD 70,000 - 98,000; Full time

Job summary

BioPhase seeks a Research Associate to join its In Vitro Biology group in San Diego. You will support evaluation of siRNA and ASO compounds using molecular biology, cell-based assays, and measurements of drug activity.

The role requires hands-on laboratory work, good collaboration with scientists, and ability to interpret data to guide early-stage research decisions in a dynamic environment.

Qualifications

• Bachelor's or master's degree in a relevant life sciences discipline.
• At least two years of laboratory experience.
• Familiarity with ELISA, siRNA, antisense oligonucleotides, and gene silencing.
• Relevant experience in molecular biology and cell biology.
• Ability to independently design experiments, analyze data, and interpret and present results.
• Strong written and verbal communication skills.
• Strong quantitative, computational, critical-thinking, and problem-solving skills.
• Ability to adapt to changing priorities and work effectively in an entrepreneurial, early-stage research environment.

Responsibilities

• Develop and execute in vitro assays to evaluate the effects of siRNA and antisense oligonucleotides on RNA transcripts, protein expression, and other project-specific endpoints.
• Perform molecular and cell-based assays, including RNA transfection, RNA and protein isolation, RT-qPCR, RNA sequencing, Western blotting, and fluorescence immunocytochemistry.
• Execute protein chemistry and target-validation protocols, including SDS-PAGE, ELISA, and Western blotting.
• Maintain mammalian cell cultures and support routine cell-based laboratory workflows.
• Collaborate with colleagues on experiments supporting compound validation and technology evaluation.
• Design experiments, analyze complex data, and interpret experimental findings.
• Maintain clear, accurate documentation of experimental methods, workflows, and results.
• Present findings and communicate research updates to colleagues and management.
• Support additional research activities and laboratory responsibilities as needed.

Skills

Molecular biology

Cell biology

Data analysis

Communication

Experiment design

Education

Bachelor's or Master's in Life Sciences

Tools

ELISA

RNA sequencing

RT-qPCR

SDS-PAGE

Western blot

RNA transfection

Job description

BioPhase seeks a Research Associate to join its In Vitro Biology group in San Diego. You will support evaluation of siRNA and ASO compounds using molecular biology, cell-based assays, and measurements of drug activity.

The role requires hands-on laboratory work, good collaboration with scientists, and ability to interpret data to guide early-stage research decisions in a dynamic environment.