Research Associate II In Vivo Pharmacology

MEDICILON USA CORP; Lexington (MA); In loco; USD 65.000 - 75.000; Tempo pieno

Descrizione del lavoro

Medicilon USA is seeking a Research Associate II to support preclinical in vivo pharmacology and disease model studies in a fast-paced CRO environment. You will perform rodent handling, dosing, sample collection, and data documentation to ensure high-quality study conduct and adherence to timelines.

The role works with study scientists and project teams to ensure compliance with animal welfare and regulatory requirements, while maintaining detailed records and supporting protocol execution.

Competenze

• Bachelor's degree in Biology, Animal Science, Life Sciences, or a related scientific discipline.
• 1–3 years of hands-on in vivo experience in a CRO, biotechnology, or pharmaceutical environment.
• Experience with rodent handling, restraint, dosing, and animal monitoring.
• Experience administering compounds through oral gavage, IV, SC, and IP routes.
• Experience with blood collection, tissue collection, necropsy, and sample processing.

Mansioni

• Perform routine animal handling, restraint, dosing, monitoring, and sample collection activities in rodent models.
• Prepare test article formulations and perform dose calculations according to study protocols.
• Administer compounds through oral gavage, IV, SC, and IP administration.
• Conduct blood collection, tissue collection, necropsy, and other study-related procedures.
• Perform protocol-specific assessments, including body weight collection, clinical observations, disease scoring, and other in-life measurements.
• Maintain accurate records of procedures, observations, and study data in notebooks and electronic systems.
• Ensure studies are conducted per approved protocols, IACUC requirements, SOPs, and company policies.
• Monitor animal health and welfare and communicate concerns to management and veterinary staff.

Conoscenze

Rodent handling

Dosing administration

Data documentation

CRO/pharma experience

IACUC compliance

Formazione

Bachelor's degree in Biology, Animal Science, Life Sciences, or related field

Descrizione del lavoro

Medicilon USA is seeking a Research Associate II to support the execution of preclinical in vivo pharmacology and disease model studies. The successful candidate will have hands‑on experience conducting rodent studies in a CRO, biotechnology, or pharmaceutical environment and will be responsible for study execution, animal procedures, sample collection, and data documentation.

This position works closely with study scientists and project teams to ensure high-quality study conduct, adherence to timelines, and compliance with animal welfare and regulatory requirements.

Key Responsibilities

• Perform routine animal handling, restraint, dosing, monitoring, and sample collection activities in rodent models.
• Prepare test article formulations and perform dose calculations according to study protocols.
• Administer compounds through common routes including oral gavage, intravenous (IV), subcutaneous (SC), and intraperitoneal (IP) administration.
• Conduct blood collection, tissue collection, necropsy, and other study‑related procedures.
• Perform protocol‑specific assessments, including body weight collection, clinical observations, disease scoring, and other in‑life measurements.
• Support study initiation activities, including preparation of study materials, labeling, room setup, and protocol review.
• Accurately record procedures, observations, and study data in laboratory notebooks, electronic systems, and study records.
• Ensure studies are conducted in accordance with approved protocols, IACUC requirements, SOPs, and company policies.
• Monitor animal health and welfare throughout study conduct and promptly communicate concerns to study management and veterinary staff.
• Maintain laboratory equipment, supplies, and inventory required for study execution.
• Collaborate effectively with scientists and cross‑functional teams to support project timelines and deliverables.
• Participate in training activities and continuously develop technical skills and knowledge.
• Perform all activities in compliance with applicable regulations, company policies, and training requirements.
• Other duties and responsibilities as assigned.

Qualifications

Required:

• Bachelor's degree in Biology, Animal Science, Life Sciences, or a related scientific discipline.
• 1–3 years of hands‑on in vivo experience in a CRO, biotechnology, pharmaceutical, or related industry environment.
• Experience with rodent handling, restraint, dosing, and animal monitoring.
• Experience administering compounds through common routes including oral gavage, intravenous (IV), subcutaneous (SC), and intraperitoneal (IP) injection.
• Experience with blood collection, tissue collection, necropsy, and sample processing.
• Experience executing studies according to protocols, SOPs, and regulatory requirements.
• Familiarity with IACUC requirements and animal welfare regulations.
• Experience supporting pharmacology, efficacy, or disease model studies.
• Strong attention to detail and ability to maintain accurate study documentation.
• Ability to manage multiple priorities and work effectively in a fast‑paced team environment.
• Strong communication and organizational skills.

Preferred

• ALAT certification or equivalent laboratory animal training.
• Experience working in a GLP‑regulated environment.
• Experience with immunology, inflammation, metabolic disease, or other therapeutic areas.
• Experience with additional in vivo techniques such as PK sampling, telemetry, surgical support, or specialized model assessments.