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Research Associate - Histology

Regel Therapeutics

Cambridge (MA)

On-site

USD 70,000 - 74,000

Full time

3 days ago
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Job summary

Regel Therapeutics, a startup in gene modulation therapy, seeks a Research Associate in Cambridge, MA. This role involves conducting histological analyses, establishing screening methodologies, and contributing to significant R&D efforts in improving gene expression for patients suffering from related disorders.

Qualifications

  • 1-3 years relevant research experience in lab setting.
  • Experience with tissue sectioning.
  • Experience with immunohistochemistry and microscopy.

Responsibilities

  • Perform histological analysis of tissues from in vivo preclinical studies.
  • Establish and implement in vivo screening methodology.
  • Validate hits using histological and molecular techniques.

Skills

Communication
Teamwork

Education

BA/BS or MS in biology, neurobiology or related field

Tools

Adobe Photoshop
Adobe Illustrator
Zeiss Zen
FIJI

Job description

This range is provided by Regel Therapeutics. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$70,000.00/yr - $74,000.00/yr

Regel Therapeutics is a gene modulation therapy company focused on improving the life of patients suffering from disorders resulting from alteration of gene expression. Our proven T3 (Targeted Therapeutic Technology) platform combines AAV delivery with two proprietary technologies for efficient and specific restoration of gene expression exclusively in the cells affected by the pathology. We are a seed-stage startup based in Cambridge, MA and Berkeley, CA and are looking for a talented Research Associate to join our R&D team and work under the guidance of senior researchers.

Location

Cambridge, MA

Role Responsibilities

  • Perform histological analysis of tissues from in vivo preclinical studies
  • Establish and implement in vivo screening methodology
  • Validate hits using histological and molecular biology techniques
  • Maintain accurate and detailed documentation of activities
  • Communicate research findings to leadership

Required Qualifications

  • BA/BS or MS in biology, neurobiology or related field with 1-3 years relevant research experience in laboratory setting
  • Experience with tissue sectioning (e.g. using a vibratome and/or cryostat)
  • Experience with immunohistochemistry and microscopy
  • Experience with performing basic analysis of experimental data
  • Excellent written and oral communication skills
  • Proven track record of working in collaborative environments

Preferred Qualifications

  • Experience with Adobe Photoshop, Adobe Illustrator, Zeiss Zen and FIJI
  • Experience with in situ hybridization and/or RNAscope
  • Previous experience working with AAVs
  • Experience extracting and analyzing nucleic acids and proteins from animal tissue
  • Experience with standard molecular biology techniques (DNA/RNA extraction, PCR, qPCR, dPCR, ddPCRetc.)
  • Experience with protein extraction, analysis, and associated biochemical techniques (Western Blot, ELISA, etc.)
Seniority level
  • Seniority level
    Not Applicable
Employment type
  • Employment type
    Full-time
Job function
  • Job function
    Research, Analyst, and Information Technology

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