Research Associate

Apollopros; South San Francisco (CA); On-site; USD 85,000 - 110,000; Full time

Job summary

Apollopros is seeking a Research Associate to support purification activities for drug discovery compounds. You will develop and optimize HPLC purification methods, analyze data, and troubleshoot purification workflows in collaboration with medicinal chemists and cross-functional teams.

The role emphasizes staying current with purification techniques and utilizing HPLC, LC-MS, and laboratory automation systems to advance discovery programs.

Qualifications

• Strong theoretical and practical knowledge in organic and analytical chemistry.
• Experience with chromatography and purification methods.
• Ability to analyze and interpret experimental data.

Responsibilities

• Support purification activities for drug discovery compounds using preparative HPLC and related technologies.
• Develop, optimize, and execute HPLC purification methods.
• Analyze, summarize, and interpret experimental data to support project objectives.
• Troubleshoot chromatography methods, instrumentation, and purification workflows.
• Collaborate with medicinal chemists and cross‑functional teams to advance discovery programs.
• Present scientific findings, results, and recommendations in meetings.
• Stay current with purification techniques, analytical tools, and industry best practices.
• Utilize HPLC, LC-MS, and laboratory automation systems.

Skills

Chromatography techniques

Analytical Chemistry

Organic Chemistry

Education

Bachelor's or Master's in Chemistry/Biochemistry or related

Tools

HPLC

LC-MS

Laboratory automation systems

Job description

Key Responsibilities

• Support purification activities for drug discovery compounds using preparative HPLC and related technologies.


• Develop, optimize, and execute HPLC purification methods.


• Analyze, summarize, and interpret experimental data to support project objectives.


• Troubleshoot chromatography methods, instrumentation, and purification workflows.


• Collaborate closely with medicinal chemists and cross‑functional research teams to advance discovery programs.


• Present scientific findings, results, and recommendations during team and group meetings.


• Stay current with emerging purification techniques, analytical tools, and industry best practices.


• Utilize advanced laboratory technologies, including: High-Performance Liquid Chromatography (HPLC) Liquid Chromatography-Mass Spectrometry (LC-MS) Laboratory automation systems


• Contribute to a culture of innovation, teamwork, and scientific excellence.

Required Qualifications

• Education Bachelor's or Master's degree in: Chemistry Biochemistry Related scientific discipline


• Technical Expertise Strong theoretical knowledge of: Organic Chemistry Analytical Chemistry


• Hands‑on experience with chromatography techniques, including: Reverse Phase (RP) Normal Phase (NP) Ion Exchange Chromatography (IEX) Solid Phase Extraction (SPE)


• Experience with analytical characterization tools such as: Mass Spectrometry (MS) Nuclear Magnetic Resonance (NMR)


• Professional Skills Ability to thrive in a fast‑paced research environment. Highly organized with strong attention to detail. Excellent time management and multitasking abilities. Strong problem‑solving and troubleshooting skills. Effective verbal and written communication skills. Ability to work both independently and collaboratively within a team environment. Demonstrated accountability, initiative, and scientific curiosity.

Preferred Qualifications

• Certification in Clinical Research.


• Experience supporting discovery chemistry, medicinal chemistry, pharmaceutical research, or drug development programs.


• Familiarity with automated laboratory systems and high‑throughput workflows.

Why Join This Opportunity?

This role offers the opportunity to work alongside accomplished scientists while contributing to the discovery of novel therapeutics. You'll gain hands‑on experience with advanced purification platforms, modern analytical technologies, and innovative drug discovery approaches in a collaborative and scientifically driven environment.

Keywords: Research Associate, Discovery Chemistry, Small Molecule Drug Discovery, HPLC, Preparative HPLC, LC-MS, Mass Spectrometry, Chromatography, Organic Chemistry, Analytical Chemistry, Medicinal Chemistry, Pharmaceutical Research, Drug Discovery, Peptide Purification, Macrocycle Research, Biochemistry, Laboratory Automation, Contract Research Associate, Chemistry Jobs.