Research Associate

Integrated Resources, Inc ( IRI ); Lexington (MA); On-site; USD 60,000 - 80,000; Full time

Job summary

A leading company is seeking a Research Associate I or II for laboratory research roles in Lexington, MA. This position focuses on executing specialized experiments in RNA isolation and drug candidate testing while contributing to multiple projects in drug discovery. Candidates should hold an Associates or Bachelor's degree with relevant experience in a lab environment, particularly in cellular biology methodologies. Strong analytical and communication skills are essential for successful collaboration within the research team.

Qualifications

• Associates degree with 1-3 years or BS/BA with 3-4 years relevant experience.
• Strong background in cellular and molecular biology, including qPCR and western blots.
• Proficiency in animal handling and data analysis expected.

Responsibilities

• Conduct siRNA screenings and perform various biological assays.
• Maintain experimental records and communicate findings effectively.
• Collaborate closely with team members to address research challenges.

Skills

Laboratory experience

RNA isolation

qPCR

Protein isolation

Western blots

Cell culture

Cell-based assays

Data analysis

Communication skills

Education

Associates degree

Bachelor's degree

Tools

Flow cytometry

Job description

JOB TITLE: Research Associate I OR II

LOCATION: Lexington, MA

DURATION: 12 months+

TOP SKILLS PER MGR:

1. Laboratory experience/ science background

2. RNA isolation and qPCR

3. Protein isolation and western blots

RNAi Platform Advancement, Nucleic Acid Research in TDAE, Client

Purpose:

To provide technical laboratory research effort in support of multiple projects focused on expedited evaluation and the clinical translation of therapies.

Essential Functions:

• Execution of siRNA tool compound screenings and structure activity relationship studies

• Cellular and molecular biology methodologies, e.g., mammalian cell culture; cell-based assays; RNA extraction and RT-qPCR; protein extraction and western blots, ELISAs and MSD assays; histological based assays including standard stains, immuno-histochemistry and in situ hybridization

• In vivo drug candidate testing (e.g., mouse dosing (SC and IV); necropsy; sample analysis)

• Analyze data and present the results in group meetings

• Maintain clear experimental records in laboratory notebooks; write SOPs and other technical reports as needed

• Work closely with research team members to quickly and effectively address critical questions related to the efficacy of our drugs

Qualifications:

• Associates degree with 1-3 years of minimum relevant technical experience (LEVEL I), BS/BA with 3-4 years of relevant drug discovery laboratory experience in pharma industry (LEVEL II)

• Previous experience in cellular and molecular biology is essential (e.g., quantitative real-time PCR, western blots) is required

• Proficiency in animal handling, dosing, and necropsy is desired

• Experience with flow cytometry or cell sorting is advantageous

• Candidate must have strong oral and written communication skills, strong work ethics and demonstrated to be an effective contributor to group projects in a team-oriented environment

• The ability to perform and interpret experiments reliably, and to advance projects aggressively towards defined goals is expected