Remote Senior Manager, Analytical Sciences

Praxis Precision Medicines, Inc.; Boston (MA); Remote; USD 115,000 - 140,000; Full time

Job summary

Praxis Precision Medicines, Inc. in the United States (remote with Boston-area travel) is seeking a Manager, Analytical Sciences for the commercial portfolio.

You will own analytical strategy, ensure testing compliance, and support lifecycle management of approved products, partnering with CDMOs across small molecule processes. The role requires hands-on technical leadership, risk assessment, method transfer/validation, and collaboration with Quality, Regulatory, Manufacturing, and CMC teams to

Qualifications

• Bachelor's degree in Chemistry or related discipline with extensive analytical experience in GMP environments.
• Experience supporting commercial small molecule drug substance/product programs.
• Strong knowledge of QA, regulatory and cGMP requirements.

Responsibilities

• Execute analytical strategies for commercial products and ensure compliant testing.
• Lead method transfer, validation, and lifecycle management activities.
• Support PPQ, CPV, commercial manufacturing, and stability programs.
• Review/approve protocols, reports, CoAs, and audit trails.
• Manage CDMO analytical activities ensuring timely, compliant deliverables.
• Lead or support investigations of OOS/OOT, deviations, and CAPAs.
• Assess analytical risks related to manufacturing and supply chain.
• Support regulatory submissions and health authority responses.
• Serve as analytical SME with Quality, Regulatory, Manufacturing, and CMC teams.

Skills

Analytical chemistry

GMP

Method transfer

Validation

Regulatory readiness

Data integrity

Cross-functional work

Education

Bachelor's degree in Chemistry or related discipline

Job description

Praxis Precision Medicines, Inc. in the United States (remote with Boston-area travel) is seeking a Manager, Analytical Sciences for the commercial portfolio.

You will own analytical strategy, ensure testing compliance, and support lifecycle management of approved products, partnering with CDMOs across small molecule processes. The role requires hands-on technical leadership, risk assessment, method transfer/validation, and collaboration with Quality, Regulatory, Manufacturing, and CMC teams to