Remote Principal Statistical Programmer – Solid Tumors

Royper Royco LLC; United States; Remote; USD 150,000 - 190,000; Full time

Job summary

ClinChoice is seeking an experienced Principal Statistical Programmer to provide leadership in solid tumor oncology programs, spanning Phase I–III, and to support regulatory submissions. The role requires deep SAS expertise, CDISC standards, and collaboration with biostatistics, data management, and clinical teams in a client-facing, remote environment.

You will mentor junior programmers, review specifications and outputs, ensure data quality, and contribute to coding standard improvements

Qualifications

• Extensive experience in clinical statistical programming within the pharmaceutical/biotech industry.
• Strong hands-on SAS programming experience including Base, Macro, and SAS/STAT.
• Experience with solid tumor oncology trials, preferably Phase I–III.
• Expertise in CDISC SDTM and ADaM standards.
• Knowledge of ICH-GCP and regulatory requirements; strong communication and collaboration skills.

Responsibilities

• Lead and oversee statistical programming activities for oncology trials, focusing on solid tumor indications.
• Develop, validate, and maintain SDTM and ADaM datasets per CDISC standards.
• Program and review complex TFLs for study reports and submissions.
• Support efficacy and safety analyses including OS, PFS, ORR, DoR, DCR.
• Provide technical leadership and mentorship to programming teams.

Skills

SAS programming

Kaplan-Meier analysis

Cox proportional hazards

SDTM/ADaM standards

Regulatory submissions

Statistical programming leadership

Cross-functional collaboration

Education

Bachelor's or Master's in Statistics/Biostatistics/Mathematics/Computer Science

Tools

SAS Base

SAS Macro

SAS/STAT

CDISC SDTM

CDISC ADaM

Job description

ClinChoice is seeking an experienced Principal Statistical Programmer to provide leadership in solid tumor oncology programs, spanning Phase I–III, and to support regulatory submissions. The role requires deep SAS expertise, CDISC standards, and collaboration with biostatistics, data management, and clinical teams in a client-facing, remote environment.

You will mentor junior programmers, review specifications and outputs, ensure data quality, and contribute to coding standard improvements