Principal Oncology Statistical Programmer — Remote Lead

ClinChoice; United States; Remote; USD 140,000 - 190,000; Full time

Job summary

ClinChoice is seeking an experienced Principal Statistical Programmer Consultant focused on solid tumor oncology, to lead programming activities across Phase I–III trials. The role emphasizes SDTM/ADaM development, CDISC standards, and regulatory submissions, with a strong emphasis on OS, PFS, ORR, and time-to-event analyses.

The ideal candidate has extensive SAS experience and can mentor junior staff while collaborating with cross-functional teams, in a remote, sponsor-facing capacity.

Qualifications

• Extensive experience in clinical statistical programming.
• Strong hands-on SAS programming skills (Base, Macro, SAS/STAT).
• Solid tumor oncology trial experience across Phases I–III.

Responsibilities

• Lead statistical programming activities for oncology trials, focusing on solid tumors.
• Develop, validate, and maintain SDTM/ADaM datasets per CDISC standards.
• Program and review TFLs for study reports and regulatory submissions.
• Support efficacy and safety analyses (OS, PFS, ORR, DoR, DCR).
• Demonstrate time-to-event analyses (Kaplan-Meier, Cox models).
• Provide technical leadership and mentorship to junior/senior programmers.

Skills

SAS programming

Kaplan-Meier analysis

Time-to-event methods

OS/PFS/ORR/DoR analyses

Education

Bachelor's or Master's in Statistics/Biostatistics

Tools

SAS Base

SAS Macro

SAS/STAT

Job description

ClinChoice is seeking an experienced Principal Statistical Programmer Consultant focused on solid tumor oncology, to lead programming activities across Phase I–III trials. The role emphasizes SDTM/ADaM development, CDISC standards, and regulatory submissions, with a strong emphasis on OS, PFS, ORR, and time-to-event analyses.

The ideal candidate has extensive SAS experience and can mentor junior staff while collaborating with cross-functional teams, in a remote, sponsor-facing capacity.