Remote Principal Enterprise AI & Transformation Architect

Simulations Plus, Inc.; United States; On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Annual bonus

Fully remote work

Flexible schedules

Generous vacation policy

Affordable health coverage

Job summary

Simulations Plus, Inc. seeks a Principal Enterprise AI and Transformation Architect to lead hands-on design, development, and delivery of AI, automation, and enterprise integration initiatives.

You will architect end-to-end solutions, prototype rapidly, and mentor teams while engaging with executives to drive strategic transformations. The role emphasizes hands-on delivery, evaluating capabilities, and delivering production-ready solutions with governance and security in mind.

Qualifications

• 8+ years of experience spanning business transformation, enterprise systems, solution architecture, intelligent automation, systems integration, AI enablement, or consulting roles.
• Hands-on experience designing, configuring, building, integrating, testing, deploying, and supporting enterprise solutions.
• Hands-on experience building AI-enabled workflows, copilots, intelligent agents, retrieval-augmented solutions, or generative AI applications.
• Hands-on experience configuring and integrating enterprise business systems and low-code platforms, such as ERP, CRM, Microsoft Power Platform, Copilot Studio, Dynamics, Salesforce, Freshworks, or comparable technologies.
• Hands-on experience designing, building, and troubleshooting API-based integrations, including REST APIs, authentication, data flows, integration patterns, connectors, and event-driven processes.
• Ability to translate ambiguous business challenges into technical solutions, working prototypes, and production implementations.
• Experience designing human + AI workflows, prompts, tools, guardrails, evaluation methods, exception handling, and operational support models.
• Ability to move fluidly between executive strategy, workshop facilitation, architecture, configuration, development, testing, deployment, and support.
• Portfolio or examples demonstrating personally delivered AI, automation, integration, or enterprise system solutions strongly preferred.
• Excellent executive communication, facilitation documentation, presentation, and stakeholder management skills.
• Experience delivering cross-functional initiatives in regulated or enterprise environments.
• Experience in life sciences, healthcare, GxP, SOX, or similarly regulated environments preferred.
• Enterprise architecture, cloud, Microsoft, AI, automation, Lean, Six Sigma, or related certifications preferred.

Responsibilities

• Partner with executives and stakeholders to translate prioritized transformation opportunities into technical solution architectures, prototypes, and implementation plans.
• Lead technical discovery and feasibility assessment for complex transformation initiatives, identifying solution options, dependencies, constraints, risks, and integration requirements.
• Translate business and process requirements into technical designs, working prototypes, implementation plans, and production solutions.
• Own the technical delivery of selected initiatives through architecture, prototyping, build, testing, deployment, and stabilization.
• Design, configure, build, test, and deploy enterprise AI workflows, copilots, intelligent agents, and automation solutions using approved platforms.
• Engineer and implement agent instructions, prompts, tools, knowledge connections, APIs, guardrails, escalation paths, evaluation and monitoring mechanisms.
• Build reusable workflows, prompt libraries, agent patterns, connectors, templates, and components that accelerate future delivery.
• Troubleshoot, tune, optimize, and support deployed solutions to improve reliability, usability, performance, and business value.
• Design and implement enterprise-system configurations, workflows, business rules, and data structures where required to deliver cross-functional transformation and AI solutions.
• Design and build API-based and platform-based integrations between ERP, CRM, financial, project management, collaboration, operational, data, automation, and AI systems.
• Solve complex technical problems involving authentication, APIs, data flows, integration logic, exception handling, automation, and AI.
• Partner with the Lead Business Systems Architect to ensure solutions align with enterprise system architecture, configuration standards, integration patterns, security requirements, and change controls.
• Transition ongoing ownership of enterprise-system configurations and integrations to the appropriate system owner following implementation and stabilization.
• Design end-to-end solutions spanning business processes, enterprise systems, data, integrations, automation platforms, and AI services.
• Develop and recommend solution architecture and platform decisions for complex transformation initiatives, balancing speed, scalability, security, compliance, maintainability, user experience, and total cost of ownership.
• Create lightweight reference patterns, design artifacts, and implementation standards based on solutions proven through hands-on delivery.
• Serve as the technical lead and escalation point for complex initiatives while remaining directly involved in prototyping and implementation.
• Rapidly build proofs of concept and working prototypes to test feasibility, demonstrate value, and reduce delivery risk.
• Convert successful prototypes into secure, supportable, production-ready solutions with appropriate testing, documentation, controls, and ownership.
• Evaluate emerging AI, automation, integration, and enterprise platform capabilities through practical experimentation.
• Recommend whether to build, buy, configure, integrate, or retire capabilities based on demonstrated business and technical fit.

Skills

Executive communication

Stakeholder management

Facilitation

Problem solving

Education

Bachelor's degree

Master's degree preferred

Advanced certifications a plus

Tools

Microsoft Power Platform

Copilot Studio

Dynamics

Salesforce

ERP

CRM

Job description

Simulations Plus, Inc. seeks a Principal Enterprise AI and Transformation Architect to lead hands-on design, development, and delivery of AI, automation, and enterprise integration initiatives.

You will architect end-to-end solutions, prototype rapidly, and mentor teams while engaging with executives to drive strategic transformations. The role emphasizes hands-on delivery, evaluating capabilities, and delivering production-ready solutions with governance and security in mind.