Remote Principal eCOA Database Programmer | Study Designer

Parexel; United States; Remote; USD 120,000 - 160,000; Full time

Job summary

Parexel is seeking a Principal Database Programmer - eCOA (eCOA Study Designer) for a fully home-based role. You will translate protocols into electronic data collection workflows, configure eCOA platforms, and ensure alignment with EDC and CRF versions across multiple projects.

The role requires strong eCOA, EDC, and global study experience, with collaboration across sponsors and internal teams to deliver high-quality patient data capture solutions.

Qualifications

• Bachelor's degree in life sciences, computer science, health informatics, clinical research or a related discipline.
• Written and oral fluency in English.
• Proven experience with eCOA, ePRO, eDiary is required.
• Strong clinical research industry experience (CRO/Pharma) is required.
• Hands-on experience configuring an eCOA platform such as Medidata Designer eCOA, or comparable study-design technology, is preferred.
• Knowledge of questionnaire design, schedules, branching logic, reminders, notifications, translations, version management, and participant workflows.
• Experience with EDC systems, preferably Medidata Rave, and understanding of eCOA-to-EDC configuration dependencies and data flow.
• Knowledge of SOPs, Work Instructions, system life-cycle methodologies, ICH-GCP, 21 CFR Part 11 and other applicable local and international regulatory requirements.
• Experience with technical quality control, UAT, defect management, change control and validated clinical systems.
• Experience supporting global studies, sponsors, and cross-functional project teams.
• Strong ability to collaborate with global, cross-functional teams and work independently across multiple time zones and cultures.
• Excellent communication skills, including the ability to explain technical design decisions to technical and non-technical audiences.
• Ability to interpret clinical protocols, schedules of assessments, questionnaires and technical specifications and translate them into system configurations.
• Proven problem-solving skills, including root-cause analysis, risk identification and decision-making in ambiguous situations.
• Customer focus and the ability to interact professionally with sponsors, vendors and internal colleagues.
• Proficient presentation and system-demonstration skills.

Responsibilities

• Design, Set Up, Maintain, Revise and Close Out eCOA Studies.
• Configure questionnaires, screens, field properties, code lists, schedules, activities, and study settings in the eCOA platform.
• Coordinate the initial eCOA configuration and controlled push to EDC; maintain alignment with CRF versions.
• Assess protocol amendments, production revisions, translations and study maintenance changes.
• Perform technical quality control of eCOA configurations and prepare UAT materials.
• Coordinate deployment readiness and communicate completion of QC and UAT prerequisites.
• Support post-production troubleshooting and controlled implementation of corrections.
• Collaborate with cross-functional teams to finalize eCOA requirements and resolve issues.

Skills

eCOA

ePRO

eDiary

Clinical research

EDC integration

Education

Bachelor's degree in life sciences or related

Tools

Medidata Designer eCOA

Medidata Rave

Job description

Parexel is seeking a Principal Database Programmer - eCOA (eCOA Study Designer) for a fully home-based role. You will translate protocols into electronic data collection workflows, configure eCOA platforms, and ensure alignment with EDC and CRF versions across multiple projects.

The role requires strong eCOA, EDC, and global study experience, with collaboration across sponsors and internal teams to deliver high-quality patient data capture solutions.