Reagent QC Analyst — HPLC, Gel & Plate Assays

Nautilus Bio; San Carlos (CA); On-site; USD 65,000 - 85,000; Full time

Job summary

Nautilus Bio, located in San Carlos, CA, is seeking a Research Associate for Reagent Quality Control to execute QC methods for incoming inspections and in-house reagent production. You will run plate-based assays, HPLC, and gel electrophoresis, supporting method development and batch documentation.

You will contribute to SOPs and development reports while collaborating with senior staff to improve QC processes. This role emphasizes data accuracy, organization, and proactive problem solving.

Qualifications

• 1+ year of industry experience with MS or 2+ years with BS in Chemistry, Biochemistry, or related field.
• Experience with HPLC and/or FPLC (AKTA), gel electrophoresis, BLI and plate-based assays.
• Ability to work independently and as part of a team.
• Desire to work in a highly cross-functional, fast-paced environment.
• Willingness to learn and grow within a transformative company.

Responsibilities

• Perform plate-based assays to support reagent QC and new reagent validation.
• Perform HPLC and gel electrophoresis to support reagent QC and new method development.
• Performing lot release, stability testing, and qualification of critical reagents.
• Collaborate with senior team members to optimize existing QC methods and develop new analytical methods.
• Ensure data quality by staying highly organized and detail-oriented and following best practices.
• Maintain and organize work areas, including hoods, benches, chemical storage, and waste disposal.
• Prepare buffers, maintaining inventory, and calibrating and maintaining laboratory instruments.
• Problem-solving: Troubleshooting failed assays or equipment malfunctions.
• Author and contribute to Standard Operating Procedures, Test Methods, Development Reports, and other documentation.

Skills

Independent worker

Team player

Cross-functional

Willingness to learn

Education

BS in Chemistry/Biochemistry

Tools

HPLC

FPLC (AKTA)

Gel electrophoresis

Plate-based assays

BLI

Job description

Nautilus Bio, located in San Carlos, CA, is seeking a Research Associate for Reagent Quality Control to execute QC methods for incoming inspections and in-house reagent production. You will run plate-based assays, HPLC, and gel electrophoresis, supporting method development and batch documentation.

You will contribute to SOPs and development reports while collaborating with senior staff to improve QC processes. This role emphasizes data accuracy, organization, and proactive problem solving.