R&D Scientist, CAR-T cell therapies

The Fountain Group; Malvern (Chester County); On-site; USD 60,000 - 80,000; Full time

Job summary

A leading company in the biopharmaceutical sector is looking for a Research and Development Scientist to support CAR-T cell therapies in Malvern, PA. This role involves developing and validating assays and maintaining cell cultures in a collaborative environment. Ideal candidates will have a strong educational background in relevant scientific fields and experience in hands-on laboratory work, particularly in immunology and cell biology.

Qualifications

• 1-2 years experience with a Master's or 3-4 years with a Bachelor's in cell biology, immunology, or related field.
• Hands-on experience with cell culture and assay methods required.
• Knowledge of ICH (Q2)R2 standards preferred.

Responsibilities

• Support CAR-T cell therapies through method development and validation.
• Plan and execute various plate-based assays like ELISA and AlphaLISA.
• Maintain culture of immortalized cell lines and manage lab inventories.

Skills

Analytical problem solving

Planning

Organizational skills

Education

Master’s degree in relevant field

Bachelor's degree in relevant field

Tools

ELISA

AlphaLISA

luciferase reporter assays

Kinexa

Biacore

MSD

Job description

Currently I have an opening for a Research and Development Scientist located in Malvern, PA.Details for the positionare as follows:

Pay Range: $28-$38/hour

Job Description:

• 2-year contract with the possibility of extending or converting to permanent based on performance and budget.
• The Advanced Therapies, Functional Potency Method Development group is seeking an energetic, highly motivated scientist to support CAR-T cell therapies. The contactor will serve as a specialist in binding assay method development and assay validation.
• Plan and execute ELISA, AlphaLISA, luciferase reporter, and other plate-based assays
• Test samples across all CAR-T cell therapy programs
• Maintain healthy cultures of immortalized cell lines according to requirements
• Help keep a large inventory of reagent stocks maintained and well organized
• Maintain good electronic lab notebook (ELN) practices to ensure proper data documentation
• Demonstrate excellent communication and interpersonal skills
• The candidate is expected to work effectively in a team environment and well as contributing individually to meet project objectives and timelines.
• Other duties to be assigned as necessary.

Qualifications:

• Master’s degree with at least 1-2+ years of experience or

bachelor's degree with at least 3-4+ years’ experience in an appropriate scientific discipline (cell biology, immunology, biological science, or related field).

• Prior experience with immortalized cell culture (adherent and suspension cells)
• Prior experience with cell counting
• Prior experience running plate-based methods (e.g. ELISA, AlphaLISA, MSD, and luciferase reporter assays)
• Strong analytical problem solving, planning and organizational skills

Preferred:

• Hands-on experience with CAR-T or other cell and gene therapy products
• Experience with co-culture functional assays in immuno oncology
• Experience in analytical method development
• Experience in analytical method qualification and validation
• Experience with Kinexa and Biacore
• Experience with MSD
• Knowledge of ICH (Q2)R2 standards.