Proteins Analytical Development Scientist (LC-MS)

6084-Janssen Research & Development, LLC Legal Entity

Malvern (Chester County)

On-site

USD 110,000 - 150,000

Full time

4 days ago

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Job summary

Johnson & Johnson in Malvern, PA seeks a Scientist, Proteins Analytical Development to lead peptide mapping and LCMS analyses on monoclonal antibodies and biotherapeutics. You will develop and qualify analytical methods, generate robust data, and support IND/IMPD filings with cross-functional teams.

You will operate state-of-the-art LC and MS instruments, learn LCMS software, and design experiments to assess sequence coverage and modifications, contributing to GMP/compliant workflows.

Qualifications

Advanced degree with LC-MS experience and strong data interpretation.
Experience with peptide mapping and method development.
Strong scientific writing, documentation and communication skills.

Responsibilities

Operate state-of-the-art LC and MS instrumentation.
Learn and apply LCMS software for protein analysis.
Perform LCMS quantification of post-translational modifications.
Design peptide mapping/MS experiments on antibodies and proteins.
Support IND/IMPD, BLA filings with data packages.
Develop test methods and write scientific reports.
Collaborate in cross-functional teams and project meetings.

Skills

Analytical reasoning

Biochemistry

Chemistry

Molecular diagnostics

Pharmacogenetics

Written expression

Data quality

Scientific writing

Education

Master's degree (Biochemistry/related)

Bachelor's degree (Biochemistry/related)

Tools

LC-MS

LCMS software

Job description

You will operate state-of-the-art LC and MS instruments, learn LCMS software, and design experiments to assess sequence coverage and modifications, contributing to GMP/compliant workflows.

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