Protein Purification Scientist

Insight Global; Collegeville (PA); Presencial; USD 58.000 - 65.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

PTO & holidays

Day-one benefits (medical, dental, vis

401(k) after 90 days

Descripción de la vacante

Insight Global is seeking a Cellular Biologist/Protein & Purification Scientist to join our Protein Biochemistry team in Collegeville, PA. The successful candidate will support virus generation, protein expression, and purification to deliver high-quality reagents to downstream partners in structural biology and screening.

The role requires executing established protocols and, with experience, troubleshooting complex protein preparations.

Formación

• Bachelor’s degree in Biochemistry, Molecular Biology, Biotechnology or related field.
• Demonstrated recombinant protein expression expertise and aseptic cell culture.
• Experience with data recording and basic analytics.

Responsabilidades

• Execute virus generation protocols and determine virus titers accurately.
• Maintain insect and mammalian cell strains for scalable expression.
• Cultivate various cells for recombinant protein expression and optimize cultures.
• Purify proteins using standard chromatography and assess quality via SDS‑PAGE, LCMS, and LCMS/MS.
• Record and analyze experimental data with enterprise databases and software.
• Document procedures and results in compliance with lab standards.

Conocimientos

Recombinant protein expression

Aseptic cell culture techniques

Data analysis and record keeping

Educación

Bachelor’s degree in Biochemistry / Molecular Biology / Biotechnology

Master’s degree is a plus

Herramientas

Automation platforms

LIMS

Descripción del empleo

Duration: Contracted through April 2028 + Potential Extension

Pay Rate: $42-47/hr

Job Description:

We are seeking a detail-oriented and highly organized Cellular Biologist/Protein & Purification Scientist to join our Protein Biochemistry team. The successful candidate will play a critical role in supporting virus generation, protein expression, and protein purification efforts, ensuring the delivery of high-quality protein reagents to our downstream partners in structural biology and screening. This position requires both the execution of established protocols and, depending on experience, the ability to troubleshoot complex protein preparations.

Duties:

• Execute established protocols for baculovirus and bacmam virus generation, including accurate determination of virus titers.
• Maintain key insect and mammalian cell strains to support readiness for protein expression at scale.
• Cultivate E. coli, insect, and mammalian cells for recombinant protein expression, monitoring and adjusting cultures in accordance with standardized methodologies.
• Perform protein purification utilizing standard liquid chromatography techniques, and evaluate reagent quality using protein biochemistry methods including SDS‑PAGE, LCMS, and LCMS/MS.
• Record, analyze, and manage experimental data using enterprise‑level databases and analytical software tools to ensure data integrity.
• Document experimental procedures and outcomes with precision, adhering to laboratory and regulatory standards.

Required Skills & Experience

• Bachelor’s degree in Biochemistry, Molecular Biology, Biotechnology, or a closely related discipline; a Master’s degree is a plus.
• Demonstrated expertise in recombinant protein expression and proficiency in aseptic techniques for cell culture.

Nice to Have Skills & Experience

• Experience with automation platforms and laboratory information management systems is an asset.

Compensation:

$42.00/hr to $47.00/hr

• 10 Days PTO + 6 Sick Days + 9 Company Paid Holidays Annually

Exact compensation may vary based on several factors, including skills, experience, and education.

Benefits

• Employees in this role will enjoy a comprehensive benefits package starting on day one of employment, including options for medical, dental, and vision insurance.
• Eligibility to enroll in the 401(k)-retirement plan begins after 90 days of employment.
• Additionally, employees in this role will have access to paid sick leave and other paid time off benefits as required under the applicable law of the worksite location.